Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea

Objectives This study aimed to classify coronavirus disease 2019 (COVID-19)-related deaths according to whether COVID-19 was listed as the cause of death, and to investigate the differences in demographic characteristics and risk factors for COVID-19 death classifications. Methods A total of 5,625 d...

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Main Authors: Na-Young Kim, Seong-Sun Kim, Hyun Ju Lee, Dong Hwi Kim, Boyeong Ryu, Eunjeong Shin, Donghyok Kwon
Format: Article
Language:English
Published: Korea Disease Control and Prevention Agency 2023-04-01
Series:Osong Public Health and Research Perspectives
Subjects:
Online Access:http://ophrp.org/upload/pdf/j-phrp-2022-0312.pdf
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author Na-Young Kim
Seong-Sun Kim
Hyun Ju Lee
Dong Hwi Kim
Boyeong Ryu
Eunjeong Shin
Donghyok Kwon
author_facet Na-Young Kim
Seong-Sun Kim
Hyun Ju Lee
Dong Hwi Kim
Boyeong Ryu
Eunjeong Shin
Donghyok Kwon
author_sort Na-Young Kim
collection DOAJ
description Objectives This study aimed to classify coronavirus disease 2019 (COVID-19)-related deaths according to whether COVID-19 was listed as the cause of death, and to investigate the differences in demographic characteristics and risk factors for COVID-19 death classifications. Methods A total of 5,625 deaths in South Korea among patients with confirmed COVID-19 from January 20, 2020 to December 31, 2021 were selected. Excluding false reports and unnatural deaths, 5,597 deaths were analyzed. Based on death report data, deaths were classified according to whether the cause of death was listed as COVID-19 (CD) or not (NCD). The epidemiological characteristics and causes of deaths were investigated using descriptive, univariate, and multivariate statistical analyses. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to analyze the risk factors. Results The case fatality ratio was 0.89% and increased with age. Additionally, 96.4% of the subjects had an underlying disease, and 53.4% died in winter. The proportion of NCDs was 9.3%, of whom 19.1% died at home and 39.0% were confirmed to have COVID-19 after death. Malignant neoplasms (102/416 vs. 637/4,442; OR, 1.71; 95% CI, 1.36−2.16; p<0.001) were significantly associated with NCD. Conclusion This is the first study to analyze risk factors by cause of death using COVID-19 death report data in South Korea. These results are expected to be used as evidence for establishing a death monitoring system that can collect timely information in a new infectious disease pandemic.
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spelling doaj.art-586dc5120dc2479fa4ad31200d9e95b72023-09-05T01:42:49ZengKorea Disease Control and Prevention AgencyOsong Public Health and Research Perspectives2233-60522023-04-01142899910.24171/j.phrp.2022.0312709Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of KoreaNa-Young Kim0Seong-Sun Kim1Hyun Ju Lee2Dong Hwi Kim3Boyeong Ryu4Eunjeong Shin5Donghyok Kwon6 Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of KoreaObjectives This study aimed to classify coronavirus disease 2019 (COVID-19)-related deaths according to whether COVID-19 was listed as the cause of death, and to investigate the differences in demographic characteristics and risk factors for COVID-19 death classifications. Methods A total of 5,625 deaths in South Korea among patients with confirmed COVID-19 from January 20, 2020 to December 31, 2021 were selected. Excluding false reports and unnatural deaths, 5,597 deaths were analyzed. Based on death report data, deaths were classified according to whether the cause of death was listed as COVID-19 (CD) or not (NCD). The epidemiological characteristics and causes of deaths were investigated using descriptive, univariate, and multivariate statistical analyses. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to analyze the risk factors. Results The case fatality ratio was 0.89% and increased with age. Additionally, 96.4% of the subjects had an underlying disease, and 53.4% died in winter. The proportion of NCDs was 9.3%, of whom 19.1% died at home and 39.0% were confirmed to have COVID-19 after death. Malignant neoplasms (102/416 vs. 637/4,442; OR, 1.71; 95% CI, 1.36−2.16; p<0.001) were significantly associated with NCD. Conclusion This is the first study to analyze risk factors by cause of death using COVID-19 death report data in South Korea. These results are expected to be used as evidence for establishing a death monitoring system that can collect timely information in a new infectious disease pandemic.http://ophrp.org/upload/pdf/j-phrp-2022-0312.pdfcovid-19deathrepublic of korearisk factors
spellingShingle Na-Young Kim
Seong-Sun Kim
Hyun Ju Lee
Dong Hwi Kim
Boyeong Ryu
Eunjeong Shin
Donghyok Kwon
Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea
Osong Public Health and Research Perspectives
covid-19
death
republic of korea
risk factors
title Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea
title_full Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea
title_fullStr Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea
title_full_unstemmed Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea
title_short Risk factors for deaths associated with COVID-19 according to the cause of death classification in Republic of Korea
title_sort risk factors for deaths associated with covid 19 according to the cause of death classification in republic of korea
topic covid-19
death
republic of korea
risk factors
url http://ophrp.org/upload/pdf/j-phrp-2022-0312.pdf
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