Exercise and skeletal muscle regeneration
Skeletal muscle injury is generally caused by stimuli, such as intense resistance training, eccentric muscle contraction, muscle strain and bruising. Injured skeletal muscles are repaired within several weeks after injury, because skeletal muscle has a remarkable capacity for muscle regeneration. Ce...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Japanese Society of Physical Fitness and Sports Medicine
2012-10-01
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| Series: | Journal of Physical Fitness and Sports Medicine |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpfsm/1/3/1_537/_pdf/-char/en |
| _version_ | 1818665890809380864 |
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| author | Mitsutoshi Kurosaka Shuichi Machida |
| author_facet | Mitsutoshi Kurosaka Shuichi Machida |
| author_sort | Mitsutoshi Kurosaka |
| collection | DOAJ |
| description | Skeletal muscle injury is generally caused by stimuli, such as intense resistance training, eccentric muscle contraction, muscle strain and bruising. Injured skeletal muscles are repaired within several weeks after injury, because skeletal muscle has a remarkable capacity for muscle regeneration. Cellular and molecular events underlying the regenerative processes are mainly regulated by myogenic stem cells and inflammatory cells. The aim of this review is to summarize the current understanding of the cellular and molecular mechanisms responsible for muscle regeneration. In this review, focus will be given to the critical roles of satellite cells and macrophages during muscle regeneration. In addition, the satellite cell responses to exercise are also discussed. |
| first_indexed | 2024-12-17T05:55:50Z |
| format | Article |
| id | doaj.art-586fbc2f49b74831844cc96ce840bf1f |
| institution | Directory Open Access Journal |
| issn | 2186-8131 2186-8123 |
| language | English |
| last_indexed | 2024-12-17T05:55:50Z |
| publishDate | 2012-10-01 |
| publisher | Japanese Society of Physical Fitness and Sports Medicine |
| record_format | Article |
| series | Journal of Physical Fitness and Sports Medicine |
| spelling | doaj.art-586fbc2f49b74831844cc96ce840bf1f2022-12-21T22:01:02ZengJapanese Society of Physical Fitness and Sports MedicineJournal of Physical Fitness and Sports Medicine2186-81312186-81232012-10-011353754010.7600/jpfsm.1.537jpfsmExercise and skeletal muscle regenerationMitsutoshi Kurosaka0Shuichi Machida1School of Physical Education, Tokai UniversitySchool of Physical Education, Tokai UniversitySkeletal muscle injury is generally caused by stimuli, such as intense resistance training, eccentric muscle contraction, muscle strain and bruising. Injured skeletal muscles are repaired within several weeks after injury, because skeletal muscle has a remarkable capacity for muscle regeneration. Cellular and molecular events underlying the regenerative processes are mainly regulated by myogenic stem cells and inflammatory cells. The aim of this review is to summarize the current understanding of the cellular and molecular mechanisms responsible for muscle regeneration. In this review, focus will be given to the critical roles of satellite cells and macrophages during muscle regeneration. In addition, the satellite cell responses to exercise are also discussed.https://www.jstage.jst.go.jp/article/jpfsm/1/3/1_537/_pdf/-char/enmuscle regenerationsatellite cellmacrophagemyokine |
| spellingShingle | Mitsutoshi Kurosaka Shuichi Machida Exercise and skeletal muscle regeneration Journal of Physical Fitness and Sports Medicine muscle regeneration satellite cell macrophage myokine |
| title | Exercise and skeletal muscle regeneration |
| title_full | Exercise and skeletal muscle regeneration |
| title_fullStr | Exercise and skeletal muscle regeneration |
| title_full_unstemmed | Exercise and skeletal muscle regeneration |
| title_short | Exercise and skeletal muscle regeneration |
| title_sort | exercise and skeletal muscle regeneration |
| topic | muscle regeneration satellite cell macrophage myokine |
| url | https://www.jstage.jst.go.jp/article/jpfsm/1/3/1_537/_pdf/-char/en |
| work_keys_str_mv | AT mitsutoshikurosaka exerciseandskeletalmuscleregeneration AT shuichimachida exerciseandskeletalmuscleregeneration |