Testicular Lymphoma: A Rare Entity
Testicular malignancy in old age men should be thoroughly studied because of low rate of incidence. Incidence of testicular lymphomas have been shown to be nearly 9% among all testicular malignancies and 1-2% of all lymphomas found in human body. The most common hisopathological pattern among lymp...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2020-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/14253/45987_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdf |
| Summary: | Testicular malignancy in old age men should be thoroughly studied because of low rate of incidence. Incidence of testicular
lymphomas have been shown to be nearly 9% among all testicular malignancies and 1-2% of all lymphomas found in human
body. The most common hisopathological pattern among lymphomas is B-cell type and of these diffuse large B-cell subtype is
commonest; however, less commonly, Burkitt’s lymphoma, anaplastic lymphoma or Hodgkin’s lymphoma may primarily involve the
testis. Testicular lymphoma is rare whether as a primary or as a secondary origin. Diffuse Large B-Cell Lymphomas (DLBCL) is the
most common histopathological type if primary in origin; however aggressive patterns like, Burkitt’s lymphoma, are more common
when there is secondary involvement of testis. Stage of the lymphoma (Ann Arbor staging) determines the prognosis of the disease.
Other prognostic factors include presence of B symptoms and International Prognostic Index (IPI) score, involvement of spermatic
cord and other testis. Immunohistochemistry should be done after histopathological diagnosis for effective treatment of variants
of testicular lymphoma. High inguinal orchiectomy along with chemotherapy with or without radiotherapy is current treatment
of choice for these tumours. In this article, the case of testicular lymphoma is presented in a 61-year-old male patient, clinical
presentation, investigations and surgical and chemotherapeutic management with discussion with respect to previous clinical
studies. In this case report, patient presented with swelling of left scrotum for which he underwent the radiological and biochemical
investigations. He was further planned for frozen section biopsy. The histopathological and immunohistochemical analysis was
suggestive of DLBCL, as final diagnosis. |
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| ISSN: | 2249-782X 0973-709X |