Selective Integrin α<sub>5</sub>β<sub>1</sub> Targeting through Spatially Constrained Multivalent DNA-Based Nanoparticles

Selective Integrin α<sub>5</sub>β<sub>1</sub> Targeting through Spatially Constrained Multivalent DNA-Based Nanoparticles

Targeting cells specifically based on receptor expression levels remains an area of active research to date. Selective binding of receptors cannot be achieved by increasing the individual binding strength, as this does not account for differing distributions of receptor density across healthy and di...

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Bibliographic Details
Main Authors: Eva E. Kurisinkal, Vincenzo Caroprese, Marianna M. Koga, Diana Morzy, Maartje M. C. Bastings
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
selective targeting
spatial tolerance
DNA nanotechnology
integrins
multivalency
Online Access:https://www.mdpi.com/1420-3049/27/15/4968

Internet

https://www.mdpi.com/1420-3049/27/15/4968

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