Ibuprofen promotes p75 neurotrophin receptor expression through modifying promoter methylation and N6-methyladenosine-RNA-methylation in human gastric cancer cells

ABSTRACTIt is acknowledged that nonsteroidal anti-inflammatory drugs (NSAIDs) can participate in various signaling pathways, while information about their epigenetic effects are limited. p75NTR (p75 neurotrophin receptor) can inhibit tumor growth by inducing cell cycle arrest and regulating cell cyc...

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Bibliographic Details
Main Authors: Haifeng Jin, Zheng Wu, Bibo Tan, Zhen Liu, Zhanfei Zu, Xiaoyun Wu, Yuwang Bi, Xingmao Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-06-01
Series:Bioengineered
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2022.2092674