Increasing productivity of arylsulfatase B-producing cell line by coexpression of formylglycine-generating enzyme

Increasing productivity of arylsulfatase B-producing cell line by coexpression of formylglycine-generating enzyme

Mucopolysaccharidosis type VI (Maroteaux–Lamy syndrome) is an orphan genetic disease caused by deficiency of the lysosomal enzyme arylsulfatase B (ASB). The need to develop a highly productive cell line for the production of recombinant ASB, is behind the concept and relevance of this study. The mos...

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Bibliographic Details
Main Authors:	S. S. Timonova, K. A. Smolova, D. T. Zaripova, M. S. Pantyushenko, M. A. Koroleva, R. L. Anisimov, R. A. Khamitov, A. A. Piskunov, V. N. Bade
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2022-04-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	cho cell line arylsulfatase b galsulfase arsb gene lysosomal enzyme sulfatase mucopolysaccharidosis type vi formylglycine-generating enzyme
Online Access:	https://www.biopreparations.ru/jour/article/view/416

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