GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

Summary: The transcriptional factor GATA2 is required for blood and hematopoietic stem cell formation during the hemogenic endothelium (HE) stage of development in the embryo. However, it is unclear if GATA2 controls HE lineage specification or if it solely regulates endothelial-to-hematopoietic tra...

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Bibliographic Details
Main Authors:	HyunJun Kang, Walatta-Tseyon Mesquitta, Ho Sun Jung, Oleg V. Moskvin, James A. Thomson, Igor I. Slukvin
Format:	Article
Language:	English
Published:	Elsevier 2018-07-01
Series:	Stem Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671118302194

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