<i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022
This study aimed to update the <i>Streptococcus suis</i> serotype distribution in Spain by analysing 302 clinical isolates recovered from diseased pigs between 2020 and 2022. The main objectives were to identify prevalent serotypes, differentiate specific serotypes 1, 14, 2, and 1/2, inv...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/11/1/40 |
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| author | Máximo Petrocchi Rilo César Bernardo Gutiérrez Martín Vanessa Acebes Fernández Álvaro Aguarón Turrientes Alba González Fernández Rubén Miguélez Pérez Sonia Martínez Martínez |
| author_facet | Máximo Petrocchi Rilo César Bernardo Gutiérrez Martín Vanessa Acebes Fernández Álvaro Aguarón Turrientes Alba González Fernández Rubén Miguélez Pérez Sonia Martínez Martínez |
| author_sort | Máximo Petrocchi Rilo |
| collection | DOAJ |
| description | This study aimed to update the <i>Streptococcus suis</i> serotype distribution in Spain by analysing 302 clinical isolates recovered from diseased pigs between 2020 and 2022. The main objectives were to identify prevalent serotypes, differentiate specific serotypes 1, 14, 2, and 1/2, investigate specific genotypic and phenotypic antimicrobial resistance features, and explore associations between resistance genes and phenotypic resistances. Serotypes 9 (21.2%), 1 (16.2%), 2 (15.6%), 3 (6%), and 7 (5.6%) were the most prevalent, whereas serotypes 14 and 1/2 corresponded with 4.3% and 0.7% of all isolates. Antimicrobial resistance genes, including <i>tet</i>(O), <i>erm</i>(B), <i>lnu</i>(B), <i>lsa</i>(E), <i>tet</i>(M), and <i>mef</i>(A/E), were analysed, which were present in 85.8%, 65.2%, 7%, 7%, 6.3%, and 1% of the samples, respectively. Susceptibility testing for 18 antimicrobials revealed high resistance levels, particularly for clindamycin (88.4%), chlortetracycline (89.4%), and sulfadimethoxine (94.4%). Notably, seven significant associations (<i>p</i> < 0.0001) were detected, correlating specific antimicrobial resistance genes to the observed phenotypic resistance. These findings contribute to understanding the <i>S. suis</i> serotype distribution and its antibiotic resistance profiles in Spain, offering valuable insights for veterinary and public health efforts in managing <i>S. suis</i>-associated infections. |
| first_indexed | 2024-03-08T10:33:22Z |
| format | Article |
| id | doaj.art-58995704becd4d059420dae1e9765beb |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-08T10:33:22Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-58995704becd4d059420dae1e9765beb2024-01-26T18:45:51ZengMDPI AGVeterinary Sciences2306-73812024-01-011114010.3390/vetsci11010040<i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022Máximo Petrocchi Rilo0César Bernardo Gutiérrez Martín1Vanessa Acebes Fernández2Álvaro Aguarón Turrientes3Alba González Fernández4Rubén Miguélez Pérez5Sonia Martínez Martínez6Animal Health Department, Veterinary Medicine Faculty, University of León, Campus de Vegazana s/n, 24071 León, SpainAnimal Health Department, Veterinary Medicine Faculty, University of León, Campus de Vegazana s/n, 24071 León, SpainAnimal Health Department, Veterinary Medicine Faculty, University of León, Campus de Vegazana s/n, 24071 León, SpainLaboratorios SYVA, Avda. De Portugal s/n, 24009 León, SpainAnimal Health Department, Veterinary Medicine Faculty, University of León, Campus de Vegazana s/n, 24071 León, SpainAnimal Health Department, Veterinary Medicine Faculty, University of León, Campus de Vegazana s/n, 24071 León, SpainAnimal Health Department, Veterinary Medicine Faculty, University of León, Campus de Vegazana s/n, 24071 León, SpainThis study aimed to update the <i>Streptococcus suis</i> serotype distribution in Spain by analysing 302 clinical isolates recovered from diseased pigs between 2020 and 2022. The main objectives were to identify prevalent serotypes, differentiate specific serotypes 1, 14, 2, and 1/2, investigate specific genotypic and phenotypic antimicrobial resistance features, and explore associations between resistance genes and phenotypic resistances. Serotypes 9 (21.2%), 1 (16.2%), 2 (15.6%), 3 (6%), and 7 (5.6%) were the most prevalent, whereas serotypes 14 and 1/2 corresponded with 4.3% and 0.7% of all isolates. Antimicrobial resistance genes, including <i>tet</i>(O), <i>erm</i>(B), <i>lnu</i>(B), <i>lsa</i>(E), <i>tet</i>(M), and <i>mef</i>(A/E), were analysed, which were present in 85.8%, 65.2%, 7%, 7%, 6.3%, and 1% of the samples, respectively. Susceptibility testing for 18 antimicrobials revealed high resistance levels, particularly for clindamycin (88.4%), chlortetracycline (89.4%), and sulfadimethoxine (94.4%). Notably, seven significant associations (<i>p</i> < 0.0001) were detected, correlating specific antimicrobial resistance genes to the observed phenotypic resistance. These findings contribute to understanding the <i>S. suis</i> serotype distribution and its antibiotic resistance profiles in Spain, offering valuable insights for veterinary and public health efforts in managing <i>S. suis</i>-associated infections.https://www.mdpi.com/2306-7381/11/1/40<i>Streptococcus suis</i>swineantibiotic resistance genesantimicrobial susceptibilityserotype |
| spellingShingle | Máximo Petrocchi Rilo César Bernardo Gutiérrez Martín Vanessa Acebes Fernández Álvaro Aguarón Turrientes Alba González Fernández Rubén Miguélez Pérez Sonia Martínez Martínez <i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 Veterinary Sciences <i>Streptococcus suis</i> swine antibiotic resistance genes antimicrobial susceptibility serotype |
| title | <i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 |
| title_full | <i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 |
| title_fullStr | <i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 |
| title_full_unstemmed | <i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 |
| title_short | <i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 |
| title_sort | i streptococcus suis i research update serotype prevalence and antimicrobial resistance distribution in swine isolates recovered in spain from 2020 to 2022 |
| topic | <i>Streptococcus suis</i> swine antibiotic resistance genes antimicrobial susceptibility serotype |
| url | https://www.mdpi.com/2306-7381/11/1/40 |
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