The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns
Introduction. Diagnosis of neonatal coarctation of the aorta (CoA) still presents a challenge in routine practice because of absence of reliable morphologic and functional parameters for early detection of this congenital heart defect in newborns. Objective. The aim of this study is to iden...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2015-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791510559I.pdf |
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| author | Ilisić Tamara Parezanović Vojislav Ilić Slobodan Đukić Milan Vukomanović Goran Vulićević Irena Kalanj Jasna Mimić Branko Milovanović Vladimir Stefanović Igor Jovanović Ida |
| author_facet | Ilisić Tamara Parezanović Vojislav Ilić Slobodan Đukić Milan Vukomanović Goran Vulićević Irena Kalanj Jasna Mimić Branko Milovanović Vladimir Stefanović Igor Jovanović Ida |
| author_sort | Ilisić Tamara |
| collection | DOAJ |
| description | Introduction. Diagnosis of neonatal coarctation of the aorta (CoA) still
presents a challenge in routine practice because of absence of reliable
morphologic and functional parameters for early detection of this congenital
heart defect in newborns. Objective. The aim of this study is to identify
easy obtainable two-dimensional echocardiographic parameters for detection of
the CoA in newborns. Methods. Echocardiographic evaluation was performed in
30 newborns with CoA and 20 healthy neonates (control group). Measurements of
the proximal transverse arch (PTA), distal transverse arch (DTA), isthmus,
distance between the left common carotid artery (LCCA) at the origin of the
left subclavian artery (LSA), were obtained by two-dimensional
echocardiography. Aortic arch hypoplasia was defined using Mouleart, Karl and
Mee criteria, and Z-value. Index 1 was calculated as a ratio of DTA and
distance between origins LCCA-LSA, Index 2 was calculated as a ratio of the
ascending aorta and the distance between LCCA-LSA origins, and Index 3 was
calculated as a ratio of PTA and distance between LCCA-LSA origins. Results.
Index 1 was significantly lower in patients with CoA in comparison with
control group (0.50 vs. 1.39; p≤0.01). A cutoff point at 0.39, for Index 1,
showed a sensitivity of 92% and specificity of 99% for the diagnosis of
neonatal CoA, while cut off points at 0.69 and 0.44, for Index 2 and Index 3,
showed the highest sensitivity and specificity for the diagnosis of CoA in
newborns. Conclusion. By using these echo indexes, two-dimensional
echocardiographic aortic arch measurement becomes a simple, reliable
noninvasive method for the evaluation of aortic coarctation in newborns and
may lead to earlier diagnosis and subsequent surgical correction. |
| first_indexed | 2024-12-17T21:31:31Z |
| format | Article |
| id | doaj.art-589ce156706e4d1a80bbb86d894b6aef |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-12-17T21:31:31Z |
| publishDate | 2015-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-589ce156706e4d1a80bbb86d894b6aef2022-12-21T21:31:52ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952015-01-011439-1055956610.2298/SARH1510559I0370-81791510559IThe role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newbornsIlisić Tamara0Parezanović Vojislav1Ilić Slobodan2Đukić Milan3Vukomanović Goran4Vulićević Irena5Kalanj Jasna6Mimić Branko7Milovanović Vladimir8Stefanović Igor9Jovanović Ida10University Children’s Hospital, BelgradeUniversity Children’s Hospital, Belgrade + School of Medicine, BelgradeUniversity Children’s Hospital, Belgrade + School of Medicine, BelgradeUniversity Children’s Hospital, Belgrade + School of Medicine, BelgradeUniversity Children’s Hospital, BelgradeUniversity Children’s Hospital, BelgradeUniversity Children’s Hospital, BelgradeUniversity Children’s Hospital, BelgradeUniversity Children’s Hospital, BelgradeUniversity Children’s Hospital, BelgradeUniversity Children’s Hospital, Belgrade + School of Medicine, BelgradeIntroduction. Diagnosis of neonatal coarctation of the aorta (CoA) still presents a challenge in routine practice because of absence of reliable morphologic and functional parameters for early detection of this congenital heart defect in newborns. Objective. The aim of this study is to identify easy obtainable two-dimensional echocardiographic parameters for detection of the CoA in newborns. Methods. Echocardiographic evaluation was performed in 30 newborns with CoA and 20 healthy neonates (control group). Measurements of the proximal transverse arch (PTA), distal transverse arch (DTA), isthmus, distance between the left common carotid artery (LCCA) at the origin of the left subclavian artery (LSA), were obtained by two-dimensional echocardiography. Aortic arch hypoplasia was defined using Mouleart, Karl and Mee criteria, and Z-value. Index 1 was calculated as a ratio of DTA and distance between origins LCCA-LSA, Index 2 was calculated as a ratio of the ascending aorta and the distance between LCCA-LSA origins, and Index 3 was calculated as a ratio of PTA and distance between LCCA-LSA origins. Results. Index 1 was significantly lower in patients with CoA in comparison with control group (0.50 vs. 1.39; p≤0.01). A cutoff point at 0.39, for Index 1, showed a sensitivity of 92% and specificity of 99% for the diagnosis of neonatal CoA, while cut off points at 0.69 and 0.44, for Index 2 and Index 3, showed the highest sensitivity and specificity for the diagnosis of CoA in newborns. Conclusion. By using these echo indexes, two-dimensional echocardiographic aortic arch measurement becomes a simple, reliable noninvasive method for the evaluation of aortic coarctation in newborns and may lead to earlier diagnosis and subsequent surgical correction.http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791510559I.pdfaortic coarctationechocardiographyneonate |
| spellingShingle | Ilisić Tamara Parezanović Vojislav Ilić Slobodan Đukić Milan Vukomanović Goran Vulićević Irena Kalanj Jasna Mimić Branko Milovanović Vladimir Stefanović Igor Jovanović Ida The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns Srpski Arhiv za Celokupno Lekarstvo aortic coarctation echocardiography neonate |
| title | The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns |
| title_full | The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns |
| title_fullStr | The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns |
| title_full_unstemmed | The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns |
| title_short | The role of two-dimensional echocardiography in diagnostics of coarctation of the aorta in newborns |
| title_sort | role of two dimensional echocardiography in diagnostics of coarctation of the aorta in newborns |
| topic | aortic coarctation echocardiography neonate |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791510559I.pdf |
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