TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration.

TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration.

Limb girdle muscular dystrophy type 2H (LGMD2H) is an inherited autosomal recessive disease of skeletal muscle caused by a mutation in the TRIM32 gene. Currently its pathogenesis is entirely unclear. Typically the regeneration process of adult skeletal muscle during growth or following injury is con...

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Bibliographic Details
Main Authors: Sarah Nicklas, Anthony Otto, Xiaoli Wu, Pamela Miller, Sandra Stelzer, Yefei Wen, Shihuan Kuang, Klaus Wrogemann, Ketan Patel, Hao Ding, Jens C Schwamborn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3267731?pdf=render

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