The role of natural killer T cells in dendritic cell licensing, cross-priming and memory CD8+ T cell generation

The role of natural killer T cells in dendritic cell licensing, cross-priming and memory CD8+ T cell generation

New vaccination strategies focus on achieving CD8+ T cell (CTL) immunity rather than on induction of protective antibody responses. While the requirement of CD4+ T (Th) cell help in dendritic cell (DC) activation and licensing, and in CTL memory induction has been described in several disease models...

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Bibliographic Details
Main Authors: Catherine eGottschalk, Elisabeth eMettke, Christian eKurts
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Immunology
Subjects:
Chemokines
Dendritic Cells
Memory
CD8 T cells
cross-presentation
Licensing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00379/full

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