Validation of the T86I mutation in the gyrA gene as a highly reliable real time PCR target to detect Fluoroquinolone-resistant Campylobacter jejuni
Abstract Background Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and increasing rates of fluoroquinolone (FQ) resistance in C. jejuni are a major public health concern. The rapid detection and tracking of FQ resistance are critical needs in developing countries, as these...
Main Authors: | Nereyda Espinoza, Jesús Rojas, Simon Pollett, Rina Meza, Lilian Patiño, Manuel Leiva, Máximo Camiña, Manuela Bernal, Nathanael D. Reynolds, Ryan Maves, Drake H. Tilley, Matthew Kasper, Mark P. Simons |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
|
Series: | BMC Infectious Diseases |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12879-020-05202-4 |
Similar Items
-
Droplet Digital PCR-Based Detection and Quantification of GyrA Thr-86-Ile Mutation Based Fluoroquinolone-Resistant Campylobacter jejuni
by: Yi Luo, et al.
Published: (2022-04-01) -
Fluoroquinolone resistance and mutation in gyrA gene in clinical isolates of Klebsiella pnemoniae
by: Zahra MohammadAlipour, et al.
Published: (2016-12-01) -
A fluoroquinolone resistance associated mutation in gyrA affects DNA supercoiling in Campylobacter jejuni
by: Jing eHan, et al.
Published: (2012-03-01) -
Detection of fluoroquinolone resistance in Mycobacterium tuberculosis clinical isolates as determined by gyrA/B gene mutation by using PCR technique
by: A. Salah Eldin, et al.
Published: (2012-10-01) -
Association between mutations in gyrA and parC genes of Acinetobacter baumannii clinical isolates and ciprofloxacin resistance
by: Abdollah Ardebili, et al.
Published: (2015-06-01)