Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components

This study aims to evaluate the occurrence of food allergy to peanuts in atopic dermatitis (AD) patients and to analyse the sensitization to molecular components. The complete dermatological and allergological examination including the examination of the sensitization to molecular components with Mu...

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Main Authors: J. Čelakovská, J. Bukač, R. Vaňková, J. Krejsek, C. Andrýs
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Food and Agricultural Immunology
Subjects:
Online Access:http://dx.doi.org/10.1080/09540105.2021.1911958
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author J. Čelakovská
J. Bukač
R. Vaňková
J. Krejsek
C. Andrýs
author_facet J. Čelakovská
J. Bukač
R. Vaňková
J. Krejsek
C. Andrýs
author_sort J. Čelakovská
collection DOAJ
description This study aims to evaluate the occurrence of food allergy to peanuts in atopic dermatitis (AD) patients and to analyse the sensitization to molecular components. The complete dermatological and allergological examination including the examination of the sensitization to molecular components with Multiplex ISAC testing was performed. Altogether 100 AD patients were examined – 48 men, 52 women, the average age 40.9 years. The food allergy to peanuts was confirmed in 27% patients; the majority of these patients are sensitized to PR 10 proteins (Ara h 8) and the minority to species-specific storage proteins and to non-specific lipid transfer protein (Ara h 9). In patients suffering from a clinical reaction to peanuts, the significant relation was confirmed to the sensitization to molecular components Aln g 1, Bet v 1, to molecular components of Timothy Phl p 1, 2, 4, 5, 6, 7 and to Mer a 1.
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spelling doaj.art-58a8449529a84431aecf43e7d6614d282022-12-21T23:48:37ZengTaylor & Francis GroupFood and Agricultural Immunology0954-01051465-34432021-01-0132122123610.1080/09540105.2021.19119581911958Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular componentsJ. Čelakovská0J. Bukač1R. Vaňková2J. Krejsek3C. Andrýs4Faculty Hospital and Medical Faculty of Charles UniversityMedical Faculty of Charles UniversityFaculty Hospital and Medical Faculty of Charles UniversityFaculty Hospital and Medical Faculty of Charles UniversityFaculty Hospital and Medical Faculty of Charles UniversityThis study aims to evaluate the occurrence of food allergy to peanuts in atopic dermatitis (AD) patients and to analyse the sensitization to molecular components. The complete dermatological and allergological examination including the examination of the sensitization to molecular components with Multiplex ISAC testing was performed. Altogether 100 AD patients were examined – 48 men, 52 women, the average age 40.9 years. The food allergy to peanuts was confirmed in 27% patients; the majority of these patients are sensitized to PR 10 proteins (Ara h 8) and the minority to species-specific storage proteins and to non-specific lipid transfer protein (Ara h 9). In patients suffering from a clinical reaction to peanuts, the significant relation was confirmed to the sensitization to molecular components Aln g 1, Bet v 1, to molecular components of Timothy Phl p 1, 2, 4, 5, 6, 7 and to Mer a 1.http://dx.doi.org/10.1080/09540105.2021.1911958peanuts allergymolecular componentsatopic dermatitis
spellingShingle J. Čelakovská
J. Bukač
R. Vaňková
J. Krejsek
C. Andrýs
Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components
Food and Agricultural Immunology
peanuts allergy
molecular components
atopic dermatitis
title Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components
title_full Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components
title_fullStr Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components
title_full_unstemmed Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components
title_short Peanuts allergy in atopic dermatitis patients, analysis of sensitization to molecular components
title_sort peanuts allergy in atopic dermatitis patients analysis of sensitization to molecular components
topic peanuts allergy
molecular components
atopic dermatitis
url http://dx.doi.org/10.1080/09540105.2021.1911958
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