Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments
This review considers whether a case can be made for a protective effect of inhibitors and blockers of the renin-angiotensin-aldosterone system (RAAS) on the cerebral circulation. It first looks at whether there exists a preferential effect on the cerebral circulation during a drug-induced lowering...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-04-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00022/full |
_version_ | 1818903843343171584 |
---|---|
author | Jeffrey eAtkinson |
author_facet | Jeffrey eAtkinson |
author_sort | Jeffrey eAtkinson |
collection | DOAJ |
description | This review considers whether a case can be made for a protective effect of inhibitors and blockers of the renin-angiotensin-aldosterone system (RAAS) on the cerebral circulation. It first looks at whether there exists a preferential effect on the cerebral circulation during a drug-induced lowering of high arterial blood pressure and cardiovascular morbi-mortality. It then goes on to consider background studies on the relationship between Inhibition of the RAAS and stroke. This is followed by exploration of possible new directions in the inhibition of the RAAS and its effect on stroke. |
first_indexed | 2024-12-19T20:57:59Z |
format | Article |
id | doaj.art-58ada421acb14a2298eaa3d746e430fe |
institution | Directory Open Access Journal |
issn | 1663-9812 |
language | English |
last_indexed | 2024-12-19T20:57:59Z |
publishDate | 2011-04-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Pharmacology |
spelling | doaj.art-58ada421acb14a2298eaa3d746e430fe2022-12-21T20:05:55ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122011-04-01210.3389/fphar.2011.0002210573Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developmentsJeffrey eAtkinson0Nancy UniversityThis review considers whether a case can be made for a protective effect of inhibitors and blockers of the renin-angiotensin-aldosterone system (RAAS) on the cerebral circulation. It first looks at whether there exists a preferential effect on the cerebral circulation during a drug-induced lowering of high arterial blood pressure and cardiovascular morbi-mortality. It then goes on to consider background studies on the relationship between Inhibition of the RAAS and stroke. This is followed by exploration of possible new directions in the inhibition of the RAAS and its effect on stroke.http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00022/fullBlood PressureStrokeangiotensincerebral circulationrat modelangiotensin AT1 receptor blockers |
spellingShingle | Jeffrey eAtkinson Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments Frontiers in Pharmacology Blood Pressure Stroke angiotensin cerebral circulation rat model angiotensin AT1 receptor blockers |
title | Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments |
title_full | Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments |
title_fullStr | Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments |
title_full_unstemmed | Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments |
title_short | Stroke, high blood pressure and the renin-angiotensin-aldosterone system – new developments |
title_sort | stroke high blood pressure and the renin angiotensin aldosterone system new developments |
topic | Blood Pressure Stroke angiotensin cerebral circulation rat model angiotensin AT1 receptor blockers |
url | http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00022/full |
work_keys_str_mv | AT jeffreyeatkinson strokehighbloodpressureandthereninangiotensinaldosteronesystemnewdevelopments |