Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept
Electrically evoked auditory potentials have been used to predict auditory thresholds in patients with a cochlear implant (CI). However, with exception of electrically evoked compound action potentials (eCAP), conventional extracorporeal EEG recording devices are still needed. Until now, built-in (i...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Audiology Research |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2039-4349/11/4/62 |
| _version_ | 1797506586494631936 |
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| author | Andy J. Beynon Bart M. Luijten Emmanuel A. M. Mylanus |
| author_facet | Andy J. Beynon Bart M. Luijten Emmanuel A. M. Mylanus |
| author_sort | Andy J. Beynon |
| collection | DOAJ |
| description | Electrically evoked auditory potentials have been used to predict auditory thresholds in patients with a cochlear implant (CI). However, with exception of electrically evoked compound action potentials (eCAP), conventional extracorporeal EEG recording devices are still needed. Until now, built-in (intracorporeal) back-telemetry options are limited to eCAPs. Intracorporeal recording of auditory responses beyond the cochlea is still lacking. This study describes the feasibility of obtaining longer latency cortical responses by concatenating interleaved short recording time windows used for eCAP recordings. Extracochlear reference electrodes were dedicated to record cortical responses, while intracochlear electrodes were used for stimulation, enabling intracorporeal telemetry (i.e., without an EEG device) to assess higher cortical processing in CI recipients. Simultaneous extra- and intra-corporeal recordings showed that it is feasible to obtain intracorporeal slow vertex potentials with a CI similar to those obtained by conventional extracorporeal EEG recordings. Our data demonstrate a proof of concept of closed-loop intracorporeal auditory cortical response telemetry (ICT) with a cochlear implant device. This research breaks new ground for next generation CI devices to assess higher cortical neural processing based on acute or continuous EEG telemetry to enable individualized automatic and/or adaptive CI fitting with only a CI. |
| first_indexed | 2024-03-10T04:35:39Z |
| format | Article |
| id | doaj.art-58b043ce5e8e4ce1aa09a903c50ffe3b |
| institution | Directory Open Access Journal |
| issn | 2039-4349 |
| language | English |
| last_indexed | 2024-03-10T04:35:39Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Audiology Research |
| spelling | doaj.art-58b043ce5e8e4ce1aa09a903c50ffe3b2023-11-23T03:48:42ZengMDPI AGAudiology Research2039-43492021-12-0111469170510.3390/audiolres11040062Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of ConceptAndy J. Beynon0Bart M. Luijten1Emmanuel A. M. Mylanus2Vestibular & Auditory Evoked Potential Lab, Department Oto-Rhino-Laryngology, Head & Neck Surgery, 6525 EX Nijmegen, The NetherlandsHearing & Implants, Department Oto-Rhino-Laryngology, Head & Neck Surgery, Donders Center Medical Neuroscience, 6525 EX Nijmegen, The NetherlandsHearing & Implants, Department Oto-Rhino-Laryngology, Head & Neck Surgery, Donders Center Medical Neuroscience, 6525 EX Nijmegen, The NetherlandsElectrically evoked auditory potentials have been used to predict auditory thresholds in patients with a cochlear implant (CI). However, with exception of electrically evoked compound action potentials (eCAP), conventional extracorporeal EEG recording devices are still needed. Until now, built-in (intracorporeal) back-telemetry options are limited to eCAPs. Intracorporeal recording of auditory responses beyond the cochlea is still lacking. This study describes the feasibility of obtaining longer latency cortical responses by concatenating interleaved short recording time windows used for eCAP recordings. Extracochlear reference electrodes were dedicated to record cortical responses, while intracochlear electrodes were used for stimulation, enabling intracorporeal telemetry (i.e., without an EEG device) to assess higher cortical processing in CI recipients. Simultaneous extra- and intra-corporeal recordings showed that it is feasible to obtain intracorporeal slow vertex potentials with a CI similar to those obtained by conventional extracorporeal EEG recordings. Our data demonstrate a proof of concept of closed-loop intracorporeal auditory cortical response telemetry (ICT) with a cochlear implant device. This research breaks new ground for next generation CI devices to assess higher cortical neural processing based on acute or continuous EEG telemetry to enable individualized automatic and/or adaptive CI fitting with only a CI.https://www.mdpi.com/2039-4349/11/4/62cochlear implantneural response telemetryauditory cortical potentialsobjective measurementsintracorporeal recordingsautomated fitting |
| spellingShingle | Andy J. Beynon Bart M. Luijten Emmanuel A. M. Mylanus Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept Audiology Research cochlear implant neural response telemetry auditory cortical potentials objective measurements intracorporeal recordings automated fitting |
| title | Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept |
| title_full | Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept |
| title_fullStr | Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept |
| title_full_unstemmed | Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept |
| title_short | Intracorporeal Cortical Telemetry as a Step to Automatic Closed-Loop EEG-Based CI Fitting: A Proof of Concept |
| title_sort | intracorporeal cortical telemetry as a step to automatic closed loop eeg based ci fitting a proof of concept |
| topic | cochlear implant neural response telemetry auditory cortical potentials objective measurements intracorporeal recordings automated fitting |
| url | https://www.mdpi.com/2039-4349/11/4/62 |
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