Synergistic effects of curcumin and gamma-oryzanol solid dispersions ameliorate muscle atrophy by upregulating Nrf2 and IGF1/Insulin-Akt-mTOR activities in middle-aged rats

Muscle atrophy is a reduction of muscle mass and size that occurs after the age of 30. The effects of the solid dispersions of curcumin (CURSD) and gamma-oryzanol (GOSD) were investigated on skeletal muscle of middle-aged Sprague-Dawley rats (12 months old) and compared to young rats (4 months old)....

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Bibliographic Details
Main Authors: Pattarawadee Taengthong, Ittipon Phoungpetchara, Onrawee Khongsombat, Sakara Tunsophon
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622003887