Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind
Pectin, a natural polysaccharide, has gained increasing attention due to not only its biomaterial properties but also its biomedical activities. One of the abundant sources of pectin is mangosteen (Garcinia mangostana L.) rind. In this study, we characterized the pectin from Indonesian mangosteen ri...
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Elsevier
2019-08-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844019359596 |
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| author | Nasrul Wathoni Chu Yuan Shan Wong Yi Shan Tina Rostinawati Raden Bayu Indradi Rimadani Pratiwi Muchtaridi Muchtaridi |
| author_facet | Nasrul Wathoni Chu Yuan Shan Wong Yi Shan Tina Rostinawati Raden Bayu Indradi Rimadani Pratiwi Muchtaridi Muchtaridi |
| author_sort | Nasrul Wathoni |
| collection | DOAJ |
| description | Pectin, a natural polysaccharide, has gained increasing attention due to not only its biomaterial properties but also its biomedical activities. One of the abundant sources of pectin is mangosteen (Garcinia mangostana L.) rind. In this study, we characterized the pectin from Indonesian mangosteen rind extract and evaluated its antioxidant activity. Pectin was extracted in acid condition and evaluated its physicochemical properties by fourier transform infrared (FTIR), powder X-ray diffractometer (PXRD), water content, ash content, equivalent weight, methoxyl level and of galacturonic acid content. Furthermore, the antioxidant activity of pectin was also observed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Pectin was successfully extracted from dry weight of Indonesian mangosten rind with yield about 1,16 ± 0,17%, fine powder, brownish and odorless. FTIR and PXRD results showed that pectin from mangosteen rind extract was amorphous and similar characteristic with a commercial pectin. The chemical properties of pectin such as water content, ash content, equivalent weight, methoxyl level and of galacturonic acid level were 9.85 ± 0.12%, 3.91 ± 0.17%, 6330.76 ± 220.43 g/mol, 2.86 ± 0.05% and 75.98 ± 0.88%, respectively. In addition, pectin showed an antioxidant activity with the IC50 about 161.94 ± 31.57 ppm. These results suggest that pectin from Indonesian mangosteen rind has the potential properties as biopolymers for biomedical applications with a low-methylated pectin and a moderate antioxidant activity. |
| first_indexed | 2024-12-12T19:46:52Z |
| format | Article |
| id | doaj.art-58b9ac33c9c04a5a834d99130304f6f5 |
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| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-12T19:46:52Z |
| publishDate | 2019-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-58b9ac33c9c04a5a834d99130304f6f52022-12-22T00:14:03ZengElsevierHeliyon2405-84402019-08-0158e02299Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rindNasrul Wathoni0Chu Yuan Shan1Wong Yi Shan2Tina Rostinawati3Raden Bayu Indradi4Rimadani Pratiwi5Muchtaridi Muchtaridi6Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia; Corresponding author.Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Biology Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Biology Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, IndonesiaPectin, a natural polysaccharide, has gained increasing attention due to not only its biomaterial properties but also its biomedical activities. One of the abundant sources of pectin is mangosteen (Garcinia mangostana L.) rind. In this study, we characterized the pectin from Indonesian mangosteen rind extract and evaluated its antioxidant activity. Pectin was extracted in acid condition and evaluated its physicochemical properties by fourier transform infrared (FTIR), powder X-ray diffractometer (PXRD), water content, ash content, equivalent weight, methoxyl level and of galacturonic acid content. Furthermore, the antioxidant activity of pectin was also observed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Pectin was successfully extracted from dry weight of Indonesian mangosten rind with yield about 1,16 ± 0,17%, fine powder, brownish and odorless. FTIR and PXRD results showed that pectin from mangosteen rind extract was amorphous and similar characteristic with a commercial pectin. The chemical properties of pectin such as water content, ash content, equivalent weight, methoxyl level and of galacturonic acid level were 9.85 ± 0.12%, 3.91 ± 0.17%, 6330.76 ± 220.43 g/mol, 2.86 ± 0.05% and 75.98 ± 0.88%, respectively. In addition, pectin showed an antioxidant activity with the IC50 about 161.94 ± 31.57 ppm. These results suggest that pectin from Indonesian mangosteen rind has the potential properties as biopolymers for biomedical applications with a low-methylated pectin and a moderate antioxidant activity.http://www.sciencedirect.com/science/article/pii/S2405844019359596Materials scienceMangosteenBiopolymerAntioxidantPolysaccharidePectin |
| spellingShingle | Nasrul Wathoni Chu Yuan Shan Wong Yi Shan Tina Rostinawati Raden Bayu Indradi Rimadani Pratiwi Muchtaridi Muchtaridi Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind Heliyon Materials science Mangosteen Biopolymer Antioxidant Polysaccharide Pectin |
| title | Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind |
| title_full | Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind |
| title_fullStr | Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind |
| title_full_unstemmed | Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind |
| title_short | Characterization and antioxidant activity of pectin from Indonesian mangosteen (Garcinia mangostana L.) rind |
| title_sort | characterization and antioxidant activity of pectin from indonesian mangosteen garcinia mangostana l rind |
| topic | Materials science Mangosteen Biopolymer Antioxidant Polysaccharide Pectin |
| url | http://www.sciencedirect.com/science/article/pii/S2405844019359596 |
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