The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study.
High HIV incidence rates have been observed among pregnant and breastfeeding women in sub-Saharan Africa. Oral pre-exposure prophylaxis (PrEP) can effectively reduce HIV acquisition in women during these periods; however, understanding of its acceptability and feasibility in antenatal and postpartum...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2019-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0223487 |
| _version_ | 1819031660920832000 |
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| author | Chifundo Zimba Suzanne Maman Nora E Rosenberg Wilbroad Mutale Oliver Mweemba Wezzie Dunda Twambilile Phanga Kasapo F Chibwe Tulani Matenga Kellie Freeborn Leah Schrubbe Bellington Vwalika Benjamin H Chi |
| author_facet | Chifundo Zimba Suzanne Maman Nora E Rosenberg Wilbroad Mutale Oliver Mweemba Wezzie Dunda Twambilile Phanga Kasapo F Chibwe Tulani Matenga Kellie Freeborn Leah Schrubbe Bellington Vwalika Benjamin H Chi |
| author_sort | Chifundo Zimba |
| collection | DOAJ |
| description | High HIV incidence rates have been observed among pregnant and breastfeeding women in sub-Saharan Africa. Oral pre-exposure prophylaxis (PrEP) can effectively reduce HIV acquisition in women during these periods; however, understanding of its acceptability and feasibility in antenatal and postpartum populations remains limited. To address this gap, we conducted in-depth interviews with 90 study participants in Malawi and Zambia: 39 HIV-negative pregnant/breastfeeding women, 14 male partners, 19 healthcare workers, and 18 policymakers. Inductive and deductive approaches were used to identify themes related to PrEP. As a public health intervention, PrEP was not well-known among patients and healthcare workers; however, when it was described to participants, most expressed positive views. Concerns about safety and adherence were raised, highlighting two critical areas for community outreach. The feasibility of introducing PrEP into antenatal services was also a concern, especially if introduced within already strained health systems. Support for PrEP varied among policymakers in Malawi and Zambia, reflecting the ongoing policy discussions in their respective countries. Implementing PrEP during the pregnancy and breastfeeding periods will require addressing barriers at the individual, facility, and policy levels. Multi- level approaches should be considered in the design of new PrEP programs for antenatal and postpartum populations. |
| first_indexed | 2024-12-21T06:49:35Z |
| format | Article |
| id | doaj.art-58bc10b2f1a240aeb570fc70834369e3 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T06:49:35Z |
| publishDate | 2019-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-58bc10b2f1a240aeb570fc70834369e32022-12-21T19:12:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032019-01-011410e022348710.1371/journal.pone.0223487The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study.Chifundo ZimbaSuzanne MamanNora E RosenbergWilbroad MutaleOliver MweembaWezzie DundaTwambilile PhangaKasapo F ChibweTulani MatengaKellie FreebornLeah SchrubbeBellington VwalikaBenjamin H ChiHigh HIV incidence rates have been observed among pregnant and breastfeeding women in sub-Saharan Africa. Oral pre-exposure prophylaxis (PrEP) can effectively reduce HIV acquisition in women during these periods; however, understanding of its acceptability and feasibility in antenatal and postpartum populations remains limited. To address this gap, we conducted in-depth interviews with 90 study participants in Malawi and Zambia: 39 HIV-negative pregnant/breastfeeding women, 14 male partners, 19 healthcare workers, and 18 policymakers. Inductive and deductive approaches were used to identify themes related to PrEP. As a public health intervention, PrEP was not well-known among patients and healthcare workers; however, when it was described to participants, most expressed positive views. Concerns about safety and adherence were raised, highlighting two critical areas for community outreach. The feasibility of introducing PrEP into antenatal services was also a concern, especially if introduced within already strained health systems. Support for PrEP varied among policymakers in Malawi and Zambia, reflecting the ongoing policy discussions in their respective countries. Implementing PrEP during the pregnancy and breastfeeding periods will require addressing barriers at the individual, facility, and policy levels. Multi- level approaches should be considered in the design of new PrEP programs for antenatal and postpartum populations.https://doi.org/10.1371/journal.pone.0223487 |
| spellingShingle | Chifundo Zimba Suzanne Maman Nora E Rosenberg Wilbroad Mutale Oliver Mweemba Wezzie Dunda Twambilile Phanga Kasapo F Chibwe Tulani Matenga Kellie Freeborn Leah Schrubbe Bellington Vwalika Benjamin H Chi The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study. PLoS ONE |
| title | The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study. |
| title_full | The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study. |
| title_fullStr | The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study. |
| title_full_unstemmed | The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study. |
| title_short | The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study. |
| title_sort | landscape for hiv pre exposure prophylaxis during pregnancy and breastfeeding in malawi and zambia a qualitative study |
| url | https://doi.org/10.1371/journal.pone.0223487 |
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