Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus)
The snake fruit peel (Salacca zalacca (Gaertn.) Voss) traditionally has several health benefits, one of which is to treat diabetes mellitus. This study aimed to determine the content of secondary metabolites in the ethanolic extract of snake fruit peel and its activity on glucose and urea creatinine...
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| Format: | Article |
| Language: | English |
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Tadulako University
2021-12-01
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| Series: | Kovalen: Jurnal Riset Kimia |
| Online Access: | https://bestjournal.untad.ac.id/index.php/kovalen/article/view/15567 |
| _version_ | 1797792365094633472 |
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| author | Tien Wahyu Handayani Agustinus Widodo Risna Yanti Erdy Prasetyo Zulfaidah Joni Tandi |
| author_facet | Tien Wahyu Handayani Agustinus Widodo Risna Yanti Erdy Prasetyo Zulfaidah Joni Tandi |
| author_sort | Tien Wahyu Handayani |
| collection | DOAJ |
| description | The snake fruit peel (Salacca zalacca (Gaertn.) Voss) traditionally has several health benefits, one of which is to treat diabetes mellitus. This study aimed to determine the content of secondary metabolites in the ethanolic extract of snake fruit peel and its activity on glucose and urea creatinine levels in male white rats (Rattus norvegicus). Phytochemical screening of extracts was carried out qualitatively and quantitatively using UV-Vis Spectrophotometry. This study is a laboratory experimental study using 30 test animals divided into 6 treatment groups (normal control, negative control, positive control, 70 mg/kg BW, 140 mg/kg BW, and 280 mg/kg BW). The results showed that the ethanol extract of the bark of the salak fruit contained 7.61 %w/w alkaloids, flavonoids 0.041% w/w, tannins 1.18% w/w, and saponins 2% w/w. Ethanol extract of salak fruit peel dose of 140 mg/kg BW affected decreasing blood glucose and urea creatinine levels. The skin of the salak fruit has the potential to be further investigated as an antidiabetic. |
| first_indexed | 2024-03-13T02:33:05Z |
| format | Article |
| id | doaj.art-58bc1220a7aa4553ad48a04a42ac93b5 |
| institution | Directory Open Access Journal |
| issn | 2477-5398 |
| language | English |
| last_indexed | 2024-03-13T02:33:05Z |
| publishDate | 2021-12-01 |
| publisher | Tadulako University |
| record_format | Article |
| series | Kovalen: Jurnal Riset Kimia |
| spelling | doaj.art-58bc1220a7aa4553ad48a04a42ac93b52023-06-29T12:04:52ZengTadulako UniversityKovalen: Jurnal Riset Kimia2477-53982021-12-017316116810.22487/kovalen.2021.v7.i3.1556715567Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus)Tien Wahyu Handayani0Agustinus Widodo1Risna Yanti2Erdy Prasetyo3Zulfaidah4Joni Tandi5Program Studi S1 Farmasi, STIFA Pelita Mas PaluJurusan Farmasi, Fakultas MIPA, Universitas TadulakoProgram Studi S1 Farmasi, STIFA Pelita Mas PaluProgram Studi S1 Farmasi, STIFA Pelita Mas PaluProgram Studi S1 Farmasi, STIFA Pelita Mas PaluProgram Studi S1 Farmasi, STIFA Pelita Mas PaluThe snake fruit peel (Salacca zalacca (Gaertn.) Voss) traditionally has several health benefits, one of which is to treat diabetes mellitus. This study aimed to determine the content of secondary metabolites in the ethanolic extract of snake fruit peel and its activity on glucose and urea creatinine levels in male white rats (Rattus norvegicus). Phytochemical screening of extracts was carried out qualitatively and quantitatively using UV-Vis Spectrophotometry. This study is a laboratory experimental study using 30 test animals divided into 6 treatment groups (normal control, negative control, positive control, 70 mg/kg BW, 140 mg/kg BW, and 280 mg/kg BW). The results showed that the ethanol extract of the bark of the salak fruit contained 7.61 %w/w alkaloids, flavonoids 0.041% w/w, tannins 1.18% w/w, and saponins 2% w/w. Ethanol extract of salak fruit peel dose of 140 mg/kg BW affected decreasing blood glucose and urea creatinine levels. The skin of the salak fruit has the potential to be further investigated as an antidiabetic.https://bestjournal.untad.ac.id/index.php/kovalen/article/view/15567 |
| spellingShingle | Tien Wahyu Handayani Agustinus Widodo Risna Yanti Erdy Prasetyo Zulfaidah Joni Tandi Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus) Kovalen: Jurnal Riset Kimia |
| title | Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus) |
| title_full | Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus) |
| title_fullStr | Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus) |
| title_full_unstemmed | Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus) |
| title_short | Analisis Metabolit Sekunder dan Aktivitas Ekstrak Etanol Kulit Buah Salak (Salacca zalacca (Gaertn.) Voss) Terhadap Kadar Glukosa dan Ureum Kreatinin Tikus Putih Jantan (Rattus norvegicus) |
| title_sort | analisis metabolit sekunder dan aktivitas ekstrak etanol kulit buah salak salacca zalacca gaertn voss terhadap kadar glukosa dan ureum kreatinin tikus putih jantan rattus norvegicus |
| url | https://bestjournal.untad.ac.id/index.php/kovalen/article/view/15567 |
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