Recombinant Fusion Protein Joining E Protein Domain III of Tick-Borne Encephalitis Virus and HSP70 of Yersinia pseudotuberculosis as an Antigen for the TI-Complexes

Recombinant Fusion Protein Joining E Protein Domain III of Tick-Borne Encephalitis Virus and HSP70 of Yersinia pseudotuberculosis as an Antigen for the TI-Complexes

Domain III (DIII) of the tick-borne encephalitis virus (TBEV) protein E contains epitopes, which induce antibodies capable of neutralizing the virus. To enhance the immunogenicity of this protein, which has a low molecular weight, the aim of the present work was to express, isolate, and characterize...

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Bibliographic Details
Main Authors: Vasily Golotin, Nina Sanina, Ludmila Davydova, Natalia Chopenko, Andrey Mazeika, Manuel Roig, Valery Shnyrov, Vladimir N. Uversky, Eduard Kostetsky
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Biomolecules
Subjects:
domain III
envelope protein
HSP70
fusion protein
TBEV
flavivirus vaccine
differential scanning calorimetry
intrinsic fluorescence
Online Access:http://www.mdpi.com/2218-273X/8/3/82

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