Rilmenidine treatment in patients with mild to moderate arterial hypertension and metabolic syndrome

Efficacy, tolerability and cardioprotective properties of rilmenidine were examined in patients with mild to moderate arterial hypertension (AH). The trial involved 51 hypertensive subjects, mean age 57,7+2,5 years. After wash-out period, rilmenidine was administered in the daily dose of 1-2 mg. At...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: S. S. Yakushin, N. I. Ivankova, N. S. Sazonova, N. V. Vilesova, G. O. Ivanova
التنسيق: مقال
اللغة:Russian
منشور في: «FIRMA «SILICEA» LLC 2004-12-01
سلاسل:Российский кардиологический журнал
الموضوعات:
الوصول للمادة أونلاين:https://russjcardiol.elpub.ru/jour/article/view/2326
الوصف
الملخص:Efficacy, tolerability and cardioprotective properties of rilmenidine were examined in patients with mild to moderate arterial hypertension (AH). The trial involved 51 hypertensive subjects, mean age 57,7+2,5 years. After wash-out period, rilmenidine was administered in the daily dose of 1-2 mg. At baseline and 12 weeks later, blood pressure (BP) and heart rate (HR) dynamics was assessed by the data from 24-hour BP monitoring (BPM), echocardiography, and biochemical blood assay. Good clinical efficacy and tolerability of albarel was observed, without disturbances of lipid, carbohydrate, electrolyte, purin metabolism, functional status of liver and kidneys. Rilmenidine treatment was also associated with EchoCG parameters improvement. Rilmenidine was effective and safe in arterial hypertension treatment, demonstrating cardioprotective properties as well.
تدمد:1560-4071
2618-7620