Thyroid-Stimulating Hormone Favors Runx2-Mediated Matrix Mineralization in HOS and SaOS2 Cells: An In Vitro and In Silico Approach

Thyroid-Stimulating Hormone Favors Runx2-Mediated Matrix Mineralization in HOS and SaOS2 Cells: An In Vitro and In Silico Approach

Osteoporosis is a skeletal disease that is both systemic and silent characterized by an unbalanced activity of bone remodeling leading to bone loss. Rising evidences demonstrate that thyroid stimulating hormone (TSH) has an important role in the regulation on the metabolism of bone. However, TSH reg...

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Bibliographic Details
Main Authors: Ramajayam Govindan, Mohamed El-Sherbiny, Khalid Mohamed Morsy Ibraheem, Srinivasan Narasimhan, Mohamed EL-Dosoky Mohamed Salama, Fazil Ahmad, Selvaraj Jayaraman, Vishnu Priya Veeraraghavan, Srinivasan Vengadassalapathy, Surapaneni Krishna Mohan, Vidhya Rekha Umapathy, Gayathri Rengasamy, Shazia Fathima Jaffer Hussain, Maheshkumar Poomarimuthu, Senthilkumar Kalimuthu
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
TSH
Runx2
ALP
SaOS2
CREB
ELK1
Online Access:https://www.mdpi.com/1420-3049/27/3/613

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