Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish
Methylene blue is an FDA approved compound with a variety of pharmacologic activities. It inhibits aggregation of several amyloidogenic proteins known to be deposited in neurodegenerative diseases. Recently, it has been proposed that methylene blue shows significant beneficial effects in a phase 2 c...
Main Authors: | Frauke van Bebber, Dominik Paquet, Alexander Hruscha, Bettina Schmid, Christian Haass |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-09-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996110000951 |
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