Ginger, a Possible Candidate for the Treatment of Dementias?
As the human life expectancy increases, age-linked diseases have become more and more frequent. The worldwide increment of dementia cases demands medical solutions, but the current available drugs do not meet all the expectations. Recently the attention of the scientific community was attracted by n...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/18/5700 |
| _version_ | 1797517934504968192 |
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| author | Giovanni Schepici Valentina Contestabile Andrea Valeri Emanuela Mazzon |
| author_facet | Giovanni Schepici Valentina Contestabile Andrea Valeri Emanuela Mazzon |
| author_sort | Giovanni Schepici |
| collection | DOAJ |
| description | As the human life expectancy increases, age-linked diseases have become more and more frequent. The worldwide increment of dementia cases demands medical solutions, but the current available drugs do not meet all the expectations. Recently the attention of the scientific community was attracted by natural compounds, used in ancient medicine, known for their beneficial effects and high tolerability. This review is focused on Ginger (<i>Zingiber officinale</i>) and explore its properties against Alzheimer’s Disease and Vascular Dementia, two of the most common and devastating forms of dementia. This work resumes the beneficial effects of Ginger compounds, tested in computational in vitro and in vivo models of Alzheimer’s Disease and Vascular Dementia, along with some human tests. All these evidences suggest a potential role of the compounds of ginger not only in the treatment of the disease, but also in its prevention. |
| first_indexed | 2024-03-10T07:23:08Z |
| format | Article |
| id | doaj.art-58c4400179d545749b2ff08f9fef2dd5 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T07:23:08Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-58c4400179d545749b2ff08f9fef2dd52023-11-22T14:27:10ZengMDPI AGMolecules1420-30492021-09-012618570010.3390/molecules26185700Ginger, a Possible Candidate for the Treatment of Dementias?Giovanni Schepici0Valentina Contestabile1Andrea Valeri2Emanuela Mazzon3IRCCS Centro Neurolesi “Bonino-Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, ItalyAs the human life expectancy increases, age-linked diseases have become more and more frequent. The worldwide increment of dementia cases demands medical solutions, but the current available drugs do not meet all the expectations. Recently the attention of the scientific community was attracted by natural compounds, used in ancient medicine, known for their beneficial effects and high tolerability. This review is focused on Ginger (<i>Zingiber officinale</i>) and explore its properties against Alzheimer’s Disease and Vascular Dementia, two of the most common and devastating forms of dementia. This work resumes the beneficial effects of Ginger compounds, tested in computational in vitro and in vivo models of Alzheimer’s Disease and Vascular Dementia, along with some human tests. All these evidences suggest a potential role of the compounds of ginger not only in the treatment of the disease, but also in its prevention.https://www.mdpi.com/1420-3049/26/18/5700gingerdementianeurodegenerationneuroinflammationAlzheimer’s diseasevascular dementia |
| spellingShingle | Giovanni Schepici Valentina Contestabile Andrea Valeri Emanuela Mazzon Ginger, a Possible Candidate for the Treatment of Dementias? Molecules ginger dementia neurodegeneration neuroinflammation Alzheimer’s disease vascular dementia |
| title | Ginger, a Possible Candidate for the Treatment of Dementias? |
| title_full | Ginger, a Possible Candidate for the Treatment of Dementias? |
| title_fullStr | Ginger, a Possible Candidate for the Treatment of Dementias? |
| title_full_unstemmed | Ginger, a Possible Candidate for the Treatment of Dementias? |
| title_short | Ginger, a Possible Candidate for the Treatment of Dementias? |
| title_sort | ginger a possible candidate for the treatment of dementias |
| topic | ginger dementia neurodegeneration neuroinflammation Alzheimer’s disease vascular dementia |
| url | https://www.mdpi.com/1420-3049/26/18/5700 |
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