Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh
Abstract Objectives High prevalence of vitamin D deficiency (VDD) in children and adolescents with type 1 diabetes (T1D) was found in several epidemiological studies. The current study aimed to assess the Vitamin D status in children and adolescents with T1D and to examine the influence of the disea...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Endocrinology, Diabetes & Metabolism |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/edm2.312 |
| _version_ | 1819364670660673536 |
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| author | Bedowra Zabeen Jebun Nahar Bulbul Ahmed Samin Tayyeb Nasreen Islam Kishwar Azad |
| author_facet | Bedowra Zabeen Jebun Nahar Bulbul Ahmed Samin Tayyeb Nasreen Islam Kishwar Azad |
| author_sort | Bedowra Zabeen |
| collection | DOAJ |
| description | Abstract Objectives High prevalence of vitamin D deficiency (VDD) in children and adolescents with type 1 diabetes (T1D) was found in several epidemiological studies. The current study aimed to assess the Vitamin D status in children and adolescents with T1D and to examine the influence of the disease characteristics on vitamin D status in a specialized care centre in a tertiary hospital in Bangladesh. Methods Participants were enrolled in the cross‐sectional study at the time of a regularly scheduled visit to the CDiC Paediatric Diabetes Center in BIRDEM 2(Bangladesh Institute of Research and Rehabilitation of Diabetes Endocrine and Metabolic Disorders), a tertiary care hospital in Bangladesh. The demographic and clinical data were collected through medical records with a structured questionnaire. Results Among sixty study participants, most had inadequate levels of vitamin D: deficiency 31 (51.7%), insufficiency 14 (23.3%) and sufficiency 15 (25.0%). Participants with vitamin D deficiency (VDD) were significantly older compared to the sufficient and insufficient group (p = .029), and were residing in urban areas (p = .036) and from higher socioeconomic status (p = .014). BMI was significantly higher in VDD compared to the sufficient group (p = .040). Although we observed higher median values of daily insulin requirements and HbA1c values in patients with VDD compared to patients with vitamin D insufficiency or vitamin D sufficiency, these differences did not reach statistical significance. Conclusions The present study revealed that the prevalence of vitamin D deficiency and insufficiency among T1 diabetes children was very high. Future studies in large sample are required to assess hypovitaminosis D in youth with T1D and also the possible relating factors of vitamin D deficiency. |
| first_indexed | 2024-12-24T23:02:38Z |
| format | Article |
| id | doaj.art-58c45df329e8439f819739e9e53ac4c7 |
| institution | Directory Open Access Journal |
| issn | 2398-9238 |
| language | English |
| last_indexed | 2024-12-24T23:02:38Z |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism |
| spelling | doaj.art-58c45df329e8439f819739e9e53ac4c72022-12-21T16:35:06ZengWileyEndocrinology, Diabetes & Metabolism2398-92382022-01-0151n/an/a10.1002/edm2.312Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in BangladeshBedowra Zabeen0Jebun Nahar1Bulbul Ahmed2Samin Tayyeb3Nasreen Islam4Kishwar Azad5Department of PaediatricsLife for a child (LFAC) & Changing Diabetes in Children (CDiC) ProgrammeBangladesh Institute of Research & Rehabilitation in DiabetesEndocrine & Metabolic Disorders (BIRDEM)Diabetic Association of Bangladesh Dhaka BangladeshDepartment of Paediatrics Bangladesh Institute of Research & Rehabilitation in DiabetesEndocrine & Metabolic Disorders (BIRDEM) Dhaka BangladeshDepartment of Paediatrics Bangladesh Institute of Research & Rehabilitation in DiabetesEndocrine & Metabolic Disorders (BIRDEM) Dhaka BangladeshDepartment of PaediatricsLife for a child (LFAC) & Changing Diabetes in Children (CDiC) ProgrammeBangladesh Institute of Research & Rehabilitation in DiabetesEndocrine & Metabolic Disorders (BIRDEM)Diabetic Association of Bangladesh Dhaka BangladeshDepartment of Paediatrics Bangladesh Institute of Research & Rehabilitation in DiabetesEndocrine & Metabolic Disorders (BIRDEM) Dhaka BangladeshDepartment of PaediatricsLife for a child (LFAC) & Changing Diabetes in Children (CDiC) ProgrammeBangladesh Institute of Research & Rehabilitation in DiabetesEndocrine & Metabolic Disorders (BIRDEM)Diabetic Association of Bangladesh Dhaka BangladeshAbstract Objectives High prevalence of vitamin D deficiency (VDD) in children and adolescents with type 1 diabetes (T1D) was found in several epidemiological studies. The current study aimed to assess the Vitamin D status in children and adolescents with T1D and to examine the influence of the disease characteristics on vitamin D status in a specialized care centre in a tertiary hospital in Bangladesh. Methods Participants were enrolled in the cross‐sectional study at the time of a regularly scheduled visit to the CDiC Paediatric Diabetes Center in BIRDEM 2(Bangladesh Institute of Research and Rehabilitation of Diabetes Endocrine and Metabolic Disorders), a tertiary care hospital in Bangladesh. The demographic and clinical data were collected through medical records with a structured questionnaire. Results Among sixty study participants, most had inadequate levels of vitamin D: deficiency 31 (51.7%), insufficiency 14 (23.3%) and sufficiency 15 (25.0%). Participants with vitamin D deficiency (VDD) were significantly older compared to the sufficient and insufficient group (p = .029), and were residing in urban areas (p = .036) and from higher socioeconomic status (p = .014). BMI was significantly higher in VDD compared to the sufficient group (p = .040). Although we observed higher median values of daily insulin requirements and HbA1c values in patients with VDD compared to patients with vitamin D insufficiency or vitamin D sufficiency, these differences did not reach statistical significance. Conclusions The present study revealed that the prevalence of vitamin D deficiency and insufficiency among T1 diabetes children was very high. Future studies in large sample are required to assess hypovitaminosis D in youth with T1D and also the possible relating factors of vitamin D deficiency.https://doi.org/10.1002/edm2.312BangladeshChildren and adolescentstype 1 diabetesvitamin D |
| spellingShingle | Bedowra Zabeen Jebun Nahar Bulbul Ahmed Samin Tayyeb Nasreen Islam Kishwar Azad Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh Endocrinology, Diabetes & Metabolism Bangladesh Children and adolescents type 1 diabetes vitamin D |
| title | Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh |
| title_full | Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh |
| title_fullStr | Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh |
| title_full_unstemmed | Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh |
| title_short | Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh |
| title_sort | vitamin d status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in bangladesh |
| topic | Bangladesh Children and adolescents type 1 diabetes vitamin D |
| url | https://doi.org/10.1002/edm2.312 |
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