Quantitative temporal diffusion spectroscopy as an early imaging biomarker of radiation therapeutic response in gliomas: A preclinical proof of concept

Quantitative temporal diffusion spectroscopy as an early imaging biomarker of radiation therapeutic response in gliomas: A preclinical proof of concept

Purpose: This study aims to test the ability of quantitative temporal diffusion spectroscopy (qTDS) to assess cellular changes associated with radiation-induced cell death in a rat glioma model. Methods and Materials: Tumor response to a single fraction of 20 Gy of x-ray radiation was investigated i...

Full description

Bibliographic Details
Main Authors:	Xiaoyu Jiang, PhD, Junzhong Xu, PhD, John C. Gore, PhD
Format:	Article
Language:	English
Published:	Elsevier 2019-04-01
Series:	Advances in Radiation Oncology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452109418302367

Similar Items

Radiation-Proof Proximity Sensor
by: BV Jayawant PhD DSc, et al.
Published: (1999-04-01)

Sequential Diffusion Tensor Imaging and Magnetic Resonance Spectroscopy in Patients Undergoing Reirradiation for Progressive Diffuse Intrinsic Pontine Glioma
by: Julianna K. Bronk, MD, PhD, et al.
Published: (2022-03-01)

Preclinical Study of Radiation on Fat Flap Regeneration under Tissue-engineering Chamber: Potential Consequences for Breast Reconstruction
by: Damien Cleret, PhD, et al.
Published: (2022-12-01)

Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial
by: Laurens Liesenborghs, M.D., et al.
Published: (2021-04-01)

Biomarkers to Assess Right Heart Pressures in Recipients of a Heart Transplant: A Proof-of-Concept Study
by: Qi-Fang Huang, MD, PhD, et al.
Published: (2018-05-01)

Diffuse midline glioma with H3-K27M mutation
by: Yi-Hua Wang, Bachelor, et al.
Published: (2022-06-01)

Preclinical Ultra-High Dose Rate (FLASH) Proton Radiation Therapy System for Small Animal Studies
by: Ning Cao, PhD, et al.
Published: (2024-03-01)

Preclinical PET Neuroimaging of [C]Bexarotene
by: Benjamin H. Rotstein PhD, et al.
Published: (2016-08-01)

Adherence Promotion With Tailored Motivational Messages: Proof of Concept and Message Preferences in Older Adults
by: Shenghao Zhang PhD, et al.
Published: (2024-01-01)

Significance of perilesional T1 hyperintense areas in the differential diagnosis of primary adult-type diffuse glioma: A case report
by: Akinari Yamano, MD, et al.
Published: (2023-10-01)

Role of Radiation Therapy in the Management of Diffuse Intrinsic Pontine Glioma: A Systematic Review
by: Matthew Gallitto, BA, et al.
Published: (2019-07-01)

Educational Case: Histologic and Molecular Features of Diffuse Gliomas
by: Sarah Zhang MD, et al.
Published: (2020-04-01)

Detection of Tumor DNA in Bronchoscopic Fluids in Peripheral NSCLC: A Proof-of-Concept Study
by: Gwenaëlle Arhant, MD, et al.
Published: (2024-02-01)

KIF23 is a potential biomarker of diffuse large B cell lymphoma
by: Yuqi Gong, PhD, et al.
Published: (2022-06-01)

Is Healthcare Employment Resilient and “Recession Proof”?
by: Marcus Dillender PhD, et al.
Published: (2021-11-01)

An Automated Scoring of Clinical Asthma Score: Proof of Concept and the Future Possibility
by: Sally Al-Omar, PhD, et al.
Published: (2021-01-01)

The Relationship Between IDH1 Mutation Status and Metabolic Imaging in Nonenhancing Supratentorial Diffuse Gliomas: A C-MET PET Study
by: Nijiati Kudulaiti MD, et al.
Published: (2019-12-01)

The Efficacy and Safety of Acupuncture for Preventing Radiation Pneumonitis in Patients With Lung Cancer: A Prospective, Single-Blinded, Randomized Pilot Proof-of-Principle Study
by: Moonkyoo Kong MD, PhD, et al.
Published: (2020-02-01)

Peripheral Interventions Radiation Exposure Reduction Using a Sensor-Based Navigation System: A Proof-of-Concept Study
by: Philippe L. L’Allier, MD, et al.
Published: (2022-02-01)

A Proof-of-Concept Study on the Use of Prostate Artery Embolization Before Definitive Radiation Therapy in Prostate Cancer
by: Jeffrey Peacock, MD, et al.
Published: (2021-05-01)

Successful Proof-of-Concept for Topical Delivery of Novel Peptide ALM201 with Potential Usefulness for Treating Neovascular Eye Disorders
by: Gideon Obasanmi, PhD, et al.
Published: (2022-06-01)

Preclinical Dosimetry for Small Animal Radiation Research in Proton Therapy: A Feasibility Study
by: Fatih Biltekin, Ph.D., et al.
Published: (2023-04-01)

Functional imaging equivalence and proof of concept for image-guided adaptive radiotherapy with fixed gantry and rotating couch
by: Ilana Feain, PhD, et al.
Published: (2016-10-01)

H3 K27-altered diffuse midline glioma in adults arising from atypical regions: Two case reports and literature review
by: Narushi Sugii, MD, PhD, et al.
Published: (2024-01-01)

Lymphocyte Depletion Rate as a Biomarker of Radiation Dose to Circulating Lymphocytes During Fractionated Partial-Body Radiation Therapy
by: Susannah G. Ellsworth, MD, et al.
Published: (2022-09-01)

Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition
by: Zihang Chen PhD, et al.
Published: (2020-03-01)

Limited short-term effect of palliative radiation therapy on quantitative computed tomography-derived bone mineral density in femora with metastases
by: Florieke Eggermont, MSc, et al.
Published: (2017-01-01)

Early preclinical work with gonadotropin-releasing hormone analogues
by: Keith Gordon, Ph.D.
Published: (2023-06-01)

Synergies and Challenges in the Preclinical and Clinical Implementation of Pathology Artificial Intelligence Applications
by: Hammad A. Qureshi, PhD, et al.
Published: (2023-12-01)

Comparable Long-Term Tumor Control for Hypofractionated FLASH Versus Conventional Radiation Therapy in an Immunocompetent Rat Glioma Model
by: Elise Konradsson, MSc, et al.
Published: (2022-11-01)

A New Preclinical Model of Retinitis Pigmentosa Due to Pde6g Deficiency
by: Michelle Carmen Jentzsch, PhD, et al.
Published: (2023-12-01)

Alternative Approaches to the Assessment of the Systemic Circulation and Left Ventricular Performance: A Proof-of-Concept Study
by: Sarah Howell, BSc, MSc, et al.
Published: (2019-03-01)

Characterizing tumor response to chemotherapy at various length scales using temporal diffusion spectroscopy.
by: Junzhong Xu, et al.
Published: (2012-01-01)

Racial Differences in Diffusion of Intensity-Modulated Radiation Therapy for Localized Prostate Cancer
by: Ewan K. Cobran PhD, et al.
Published: (2016-09-01)

Oncolytic viral therapy with anti-PD-1 immunotherapy in a pediatric patient with diffuse intrinsic pontine glioma
by: M.P. Osuna Marco, M.D., et al.
Published: (2020-09-01)

Qualitative and Quantitative Research
by: Barney G. Glaser, Ph.D., Hon. Ph.D.
Published: (2008-06-01)

A patient-specific proof of concept with a three-dimensionally printed model before performing an endovascular Bentall procedure
by: Aurelien Vallée, MD, et al.
Published: (2021-12-01)

A Proof-of-Concept Pilot Test of a Behavioral Intervention to Improve Adherence to Dietary Recommendations for Cancer Prevention
by: Meghan L. Butryn PhD, et al.
Published: (2023-11-01)

Cardiac Safety Assessment of Lazertinib: Findings From Patients With EGFR Mutation-Positive Advanced NSCLC and Preclinical Studies
by: Seong Bok Jang, PhD, et al.
Published: (2021-10-01)

Evaluating of Existing VTE Risk Scales in Glioma Patients
by: Simakova Maria MD, PhD, et al.
Published: (2024-04-01)