Generation of a familial hypercholesterolemia model in non-human primate

Generation of a familial hypercholesterolemia model in non-human primate

Abstract Familial hypercholesterolemia (FH) is an inherited autosomal dominant disorder that is associated with a high plasma level of low-density lipoprotein (LDL) cholesterol, leading to an increased risk of cardiovascular diseases. To develop basic and translational research on FH, we here genera...

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Bibliographic Details
Main Authors: Akira Sato, Tomoyuki Tsukiyama, Masahiro Komeno, Chizuru Iwatani, Hideaki Tsuchiya, Ikuo Kawamoto, Mitsuru Murase, Takahiro Nakagawa, Iori Itagaki, Yasunari Seita, Shoma Matsumoto, Masataka Nakaya, Akio Shimizu, Atsushi Yamada, Masatsugu Ema, Hisakazu Ogita
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42763-1

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