Local Attraction of Substrates and Co-Substrates Enhances Weak Acid and Base Transmembrane Transport
The transmembrane transport of weak acid and base metabolites depends on the local pH conditions that affect the protonation status of the substrates and the availability of co-substrates, typically protons. Different protein designs ensure the attraction of substrates and co-substrates to the trans...
Main Authors: | Nathan Hugo Epalle, Eric Beitz |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/12/12/1794 |
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