Autophagy blockade synergistically enhances nanosonosensitizer-enabled sonodynamic cancer nanotherapeutics

Autophagy blockade synergistically enhances nanosonosensitizer-enabled sonodynamic cancer nanotherapeutics

Abstract Ultrasound-triggered sonodynamic therapy (SDT) represents an emerging therapeutic modality for cancer treatment based on its specific feature of noninvasiveness, high tissue-penetrating depth and desirable therapeutic efficacy, but the SDT-induced pro-survival cancer-cell autophagy would si...

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Bibliographic Details
Main Authors: Liqiang Zhou, Minfeng Huo, Xiaoqin Qian, Li Ding, Luodan Yu, Wei Feng, Xinwu Cui, Yu Chen
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Nanobiotechnology
Subjects:
Autophagy
Sonodynamic therapy
Autophagy inhibition
Nanoliposomes
Tumor therapy
Online Access:https://doi.org/10.1186/s12951-021-00855-y

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