Pregnane X Receptor Mediates Atherosclerosis Induced by Dicyclohexyl Phthalate in LDL Receptor-Deficient Mice

Pregnane X Receptor Mediates Atherosclerosis Induced by Dicyclohexyl Phthalate in LDL Receptor-Deficient Mice

Plastic-associated endocrine disrupting chemicals (EDCs) have been implicated in the etiology of cardiovascular disease (CVD) in humans, but the underlying mechanisms remain elusive. Dicyclohexyl phthalate (DCHP) is a widely used phthalate plasticizer; whether and how exposure to DCHP elicits advers...

Full description

Bibliographic Details
Main Authors: Jingwei Liu, Rebecca Hernandez, Xiuchun Li, Zhaojie Meng, Hong Chen, Changcheng Zhou
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
endocrine disrupting chemicals
atherosclerosis
phthalate
plastics
pregnane X receptor
Online Access:https://www.mdpi.com/2073-4409/11/7/1125

Similar Items

Similar Items