Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine
Dexmedetomidine is an alpha-2 agonist sedative and analgesic used in anesthesia practice, and it has become more prevalent in the critically ill patients requiring short-term mechanical ventilation. While dexmedetomidine is known to have minimal effects on respiratory drive, it has been well-documen...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Trauma Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352644021001539 |
| _version_ | 1818700934749880320 |
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| author | Anoosh Bahraini Oyshik Banerjee Jin Ra |
| author_facet | Anoosh Bahraini Oyshik Banerjee Jin Ra |
| author_sort | Anoosh Bahraini |
| collection | DOAJ |
| description | Dexmedetomidine is an alpha-2 agonist sedative and analgesic used in anesthesia practice, and it has become more prevalent in the critically ill patients requiring short-term mechanical ventilation. While dexmedetomidine is known to have minimal effects on respiratory drive, it has been well-documented to cause bradycardia and hypotension, especially in patients with existing comorbidities. We present a patient without cardiovascular comorbidities who was in the surgical ICU under dexmedetomidine sedation. The patient went into asystole cardiac arrest after vagal stimulation. Return of spontaneous circulation was achieved using ACLS protocol. We offer a review of reported cases and make recommendations on the management of similar situations that may arise given the increasing use of dexmedetomidine. |
| first_indexed | 2024-12-17T15:12:50Z |
| format | Article |
| id | doaj.art-58cf84b1d30949469d4d107507d1d32d |
| institution | Directory Open Access Journal |
| issn | 2352-6440 |
| language | English |
| last_indexed | 2024-12-17T15:12:50Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Trauma Case Reports |
| spelling | doaj.art-58cf84b1d30949469d4d107507d1d32d2022-12-21T21:43:37ZengElsevierTrauma Case Reports2352-64402021-12-0136100548Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidineAnoosh Bahraini0Oyshik Banerjee1Jin Ra2Corresponding author at: 201 S Elliott Rd, Apt 338, Chapel Hill, NC 27514, United States of America.; University of North Carolina Hospital at Chapel Hill, Chapel Hill, NC 27599, United States of AmericaUniversity of North Carolina Hospital at Chapel Hill, Chapel Hill, NC 27599, United States of AmericaUniversity of North Carolina Hospital at Chapel Hill, Chapel Hill, NC 27599, United States of AmericaDexmedetomidine is an alpha-2 agonist sedative and analgesic used in anesthesia practice, and it has become more prevalent in the critically ill patients requiring short-term mechanical ventilation. While dexmedetomidine is known to have minimal effects on respiratory drive, it has been well-documented to cause bradycardia and hypotension, especially in patients with existing comorbidities. We present a patient without cardiovascular comorbidities who was in the surgical ICU under dexmedetomidine sedation. The patient went into asystole cardiac arrest after vagal stimulation. Return of spontaneous circulation was achieved using ACLS protocol. We offer a review of reported cases and make recommendations on the management of similar situations that may arise given the increasing use of dexmedetomidine.http://www.sciencedirect.com/science/article/pii/S2352644021001539DexmedetomidineCardiac arrestCritically ill |
| spellingShingle | Anoosh Bahraini Oyshik Banerjee Jin Ra Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine Trauma Case Reports Dexmedetomidine Cardiac arrest Critically ill |
| title | Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine |
| title_full | Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine |
| title_fullStr | Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine |
| title_full_unstemmed | Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine |
| title_short | Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine |
| title_sort | bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine |
| topic | Dexmedetomidine Cardiac arrest Critically ill |
| url | http://www.sciencedirect.com/science/article/pii/S2352644021001539 |
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