<i>Brucella abortus</i>-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway

<i>Brucella abortus</i>-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway

Central nervous system invasion by bacteria of the genus <i>Brucella</i> results in an inflammatory disorder called neurobrucellosis. A common feature associated with this pathology is blood–brain barrier (BBB) activation. However, the underlying mechanisms involved with such BBB activat...

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Bibliographic Details
Main Authors: Ana María Rodríguez, Aldana Trotta, Agustina P. Melnyczajko, M. Cruz Miraglia, Kwang Sik Kim, M. Victoria Delpino, Paula Barrionuevo, Guillermo Hernán Giambartolomei
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pathogens
Subjects:
<i>Brucella abortus</i>
neurobrucellosis
platelets
brain microvascular endothelial cells
endothelial cells
Online Access:https://www.mdpi.com/2076-0817/9/9/708

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