Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach
Vonoprazan-associated gastric mucosal redness is rare, and its endoscopic and pathological features remain poorly described. We report 4 cases of vonoprazan-associated gastric mucosal redness, that is, 2 cases each in non-Helicobacter pylori-infected and -eradicated stomach. In all cases, esophagoga...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2021-08-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | https://www.karger.com/Article/FullText/518292 |
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| author | Kimitoshi Kubo Noriko Kimura Ryosuke Watanabe Masayuki Higashino Momoko Tsuda Mototsugu Kato |
| author_facet | Kimitoshi Kubo Noriko Kimura Ryosuke Watanabe Masayuki Higashino Momoko Tsuda Mototsugu Kato |
| author_sort | Kimitoshi Kubo |
| collection | DOAJ |
| description | Vonoprazan-associated gastric mucosal redness is rare, and its endoscopic and pathological features remain poorly described. We report 4 cases of vonoprazan-associated gastric mucosal redness, that is, 2 cases each in non-Helicobacter pylori-infected and -eradicated stomach. In all cases, esophagogastroduodenoscopy demonstrated spotty and linear redness newly appearing in the greater curvature of the gastric body after initiation of vonoprazan but disappearing after its discontinuation. A tissue biopsy taken from the gastric mucosa with redness revealed various pathological findings and included inflammatory cell infiltration, parietal cell protrusions, oxyntic gland dilatations, congestion, focal hemorrhage with congestion beneath the basement membrane, and vacuolar degeneration of parietal cells. To our knowledge, this is the second report describing the endoscopic and pathological features of vonoprazan-associated gastric mucosal redness. |
| first_indexed | 2024-12-14T00:35:18Z |
| format | Article |
| id | doaj.art-58d0d1126ef3430ca48503d4d0b3bac8 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-14T00:35:18Z |
| publishDate | 2021-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-58d0d1126ef3430ca48503d4d0b3bac82022-12-21T23:24:40ZengKarger PublishersCase Reports in Gastroenterology1662-06312021-08-0115275175810.1159/000518292518292Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated StomachKimitoshi Kubo0Noriko Kimura1Ryosuke Watanabe2Masayuki Higashino3Momoko Tsuda4Mototsugu Kato5Department of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, JapanDepartment of Pathology, National Hospital Organization Hakodate National Hospital, Hakodate, JapanDepartment of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, JapanDepartment of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, JapanDepartment of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, JapanDepartment of Gastroenterology, National Hospital Organization Hakodate National Hospital, Hakodate, JapanVonoprazan-associated gastric mucosal redness is rare, and its endoscopic and pathological features remain poorly described. We report 4 cases of vonoprazan-associated gastric mucosal redness, that is, 2 cases each in non-Helicobacter pylori-infected and -eradicated stomach. In all cases, esophagogastroduodenoscopy demonstrated spotty and linear redness newly appearing in the greater curvature of the gastric body after initiation of vonoprazan but disappearing after its discontinuation. A tissue biopsy taken from the gastric mucosa with redness revealed various pathological findings and included inflammatory cell infiltration, parietal cell protrusions, oxyntic gland dilatations, congestion, focal hemorrhage with congestion beneath the basement membrane, and vacuolar degeneration of parietal cells. To our knowledge, this is the second report describing the endoscopic and pathological features of vonoprazan-associated gastric mucosal redness.https://www.karger.com/Article/FullText/518292vonoprazanstomachgastric mucosal redness |
| spellingShingle | Kimitoshi Kubo Noriko Kimura Ryosuke Watanabe Masayuki Higashino Momoko Tsuda Mototsugu Kato Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach Case Reports in Gastroenterology vonoprazan stomach gastric mucosal redness |
| title | Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach |
| title_full | Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach |
| title_fullStr | Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach |
| title_full_unstemmed | Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach |
| title_short | Vonoprazan-Associated Gastric Mucosal Redness in Non-Helicobacter pylori-Infected and Helicobacter pylori-Eradicated Stomach |
| title_sort | vonoprazan associated gastric mucosal redness in non helicobacter pylori infected and helicobacter pylori eradicated stomach |
| topic | vonoprazan stomach gastric mucosal redness |
| url | https://www.karger.com/Article/FullText/518292 |
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