Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant

Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant

Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have adjuvant properties in generating cellular Th...

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Bibliographic Details
Main Authors: Lázaro Moreira Marques Neto, Nicholas Zufelato, Ailton Antônio de Sousa-Júnior, Monalisa Martins Trentini, Adeliane Castro da Costa, Andris Figueiroa Bakuzis, André Kipnis, Ana Paula Junqueira-Kipnis
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
infectious disease
manganese ferrite
antigenicity
th1
th17
tcd8 cells
Online Access:http://dx.doi.org/10.1080/21645515.2018.1489192

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