Breast cancer treatment by nanophotolysis approach
In this work, gold nanoparticles irradiated with nanosecond short pulse laser for breast cancer treatment is studied theoretically. Nanophotolysis is involved for selective damaging of breast cancer cells. Results shows that laser fluence of 1.5 J/cm2 interact with gold nanoparticles and generates a...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-06-01
|
| Series: | Results in Physics |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211379717325317 |
| _version_ | 1811215997823090688 |
|---|---|
| author | Muhammad Gul Bahar Ashiq |
| author_facet | Muhammad Gul Bahar Ashiq |
| author_sort | Muhammad Gul Bahar Ashiq |
| collection | DOAJ |
| description | In this work, gold nanoparticles irradiated with nanosecond short pulse laser for breast cancer treatment is studied theoretically. Nanophotolysis is involved for selective damaging of breast cancer cells. Results shows that laser fluence of 1.5 J/cm2 interact with gold nanoparticles and generates a maximum number of ions. Laser light in the visible region interacts with the gold foil. At 700 nm, 12 × 1012 ions are produced for the laser intensity of 8.89 × 107 W/cm2. Slow increase in the Coulomb explosion pressure from 0.6 × 106 Pa to 2 × 106 Pa is observed for a cluster size of range 10 nm to 20 nm. Penetration of nanobullets in tumor increases with the increase of temperature from 39.83 °C to 62.20 °C. Number of cell damaged increases by increasing the number of ions (6 × 1016 cells are damaged by 9.59 × 1020 gold ions). Findings are compared with the other experimental results and are found in excellent agreement. It is concluded from current work that nanophotolysis therapy is may be useful in future for selective damaging of breast cancer cells. |
| first_indexed | 2024-04-12T06:32:20Z |
| format | Article |
| id | doaj.art-58d3c66d70594e89bab6dce446bb2033 |
| institution | Directory Open Access Journal |
| issn | 2211-3797 |
| language | English |
| last_indexed | 2024-04-12T06:32:20Z |
| publishDate | 2018-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Physics |
| spelling | doaj.art-58d3c66d70594e89bab6dce446bb20332022-12-22T03:43:59ZengElsevierResults in Physics2211-37972018-06-019982986Breast cancer treatment by nanophotolysis approachMuhammad Gul Bahar Ashiq0Basic Engineering Sciences, College of Engineering Majmaah University, 11952 Majmaah, Saudi ArabiaIn this work, gold nanoparticles irradiated with nanosecond short pulse laser for breast cancer treatment is studied theoretically. Nanophotolysis is involved for selective damaging of breast cancer cells. Results shows that laser fluence of 1.5 J/cm2 interact with gold nanoparticles and generates a maximum number of ions. Laser light in the visible region interacts with the gold foil. At 700 nm, 12 × 1012 ions are produced for the laser intensity of 8.89 × 107 W/cm2. Slow increase in the Coulomb explosion pressure from 0.6 × 106 Pa to 2 × 106 Pa is observed for a cluster size of range 10 nm to 20 nm. Penetration of nanobullets in tumor increases with the increase of temperature from 39.83 °C to 62.20 °C. Number of cell damaged increases by increasing the number of ions (6 × 1016 cells are damaged by 9.59 × 1020 gold ions). Findings are compared with the other experimental results and are found in excellent agreement. It is concluded from current work that nanophotolysis therapy is may be useful in future for selective damaging of breast cancer cells.http://www.sciencedirect.com/science/article/pii/S2211379717325317 |
| spellingShingle | Muhammad Gul Bahar Ashiq Breast cancer treatment by nanophotolysis approach Results in Physics |
| title | Breast cancer treatment by nanophotolysis approach |
| title_full | Breast cancer treatment by nanophotolysis approach |
| title_fullStr | Breast cancer treatment by nanophotolysis approach |
| title_full_unstemmed | Breast cancer treatment by nanophotolysis approach |
| title_short | Breast cancer treatment by nanophotolysis approach |
| title_sort | breast cancer treatment by nanophotolysis approach |
| url | http://www.sciencedirect.com/science/article/pii/S2211379717325317 |
| work_keys_str_mv | AT muhammadgulbaharashiq breastcancertreatmentbynanophotolysisapproach |