Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review

This literature review rigorously examines the growing scientific interest in computational methods for Tissue Engineering and Regenerative Medicine biofabrication, a leading-edge area in biomedical innovation, emphasizing the need for accurate, multi-stage, and multi-component biofabrication proces...

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Main Authors: Roberta Bardini, Stefano Di Carlo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023005111
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author Roberta Bardini
Stefano Di Carlo
author_facet Roberta Bardini
Stefano Di Carlo
author_sort Roberta Bardini
collection DOAJ
description This literature review rigorously examines the growing scientific interest in computational methods for Tissue Engineering and Regenerative Medicine biofabrication, a leading-edge area in biomedical innovation, emphasizing the need for accurate, multi-stage, and multi-component biofabrication process models. The paper presents a comprehensive bibliometric and contextual analysis, followed by a literature review, to shed light on the vast potential of computational methods in this domain. It reveals that most existing methods focus on single biofabrication process stages and components, and there is a significant gap in approaches that utilize accurate models encompassing both biological and technological aspects. This analysis underscores the indispensable role of these methods in understanding and effectively manipulating complex biological systems and the necessity for developing computational methods that span multiple stages and components. The review concludes that such comprehensive computational methods are essential for developing innovative and efficient Tissue Engineering and Regenerative Medicine biofabrication solutions, driving forward advancements in this dynamic and evolving field.
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spelling doaj.art-58d67d6731c44e8482f8acffcbd5c88e2024-01-07T04:31:37ZengElsevierComputational and Structural Biotechnology Journal2001-03702024-12-0123601616Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature reviewRoberta Bardini0Stefano Di Carlo1Corresponding author.; Department of Control and Computer Engineering, Polytechnic University of Turin, Corso Duca Degli Abruzzi, 24, Turin, 10129, ItalyDepartment of Control and Computer Engineering, Polytechnic University of Turin, Corso Duca Degli Abruzzi, 24, Turin, 10129, ItalyThis literature review rigorously examines the growing scientific interest in computational methods for Tissue Engineering and Regenerative Medicine biofabrication, a leading-edge area in biomedical innovation, emphasizing the need for accurate, multi-stage, and multi-component biofabrication process models. The paper presents a comprehensive bibliometric and contextual analysis, followed by a literature review, to shed light on the vast potential of computational methods in this domain. It reveals that most existing methods focus on single biofabrication process stages and components, and there is a significant gap in approaches that utilize accurate models encompassing both biological and technological aspects. This analysis underscores the indispensable role of these methods in understanding and effectively manipulating complex biological systems and the necessity for developing computational methods that span multiple stages and components. The review concludes that such comprehensive computational methods are essential for developing innovative and efficient Tissue Engineering and Regenerative Medicine biofabrication solutions, driving forward advancements in this dynamic and evolving field.http://www.sciencedirect.com/science/article/pii/S2001037023005111Computational biologyOptimization via simulationBiofabricationTissue engineeringRegenerative medicine
spellingShingle Roberta Bardini
Stefano Di Carlo
Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review
Computational and Structural Biotechnology Journal
Computational biology
Optimization via simulation
Biofabrication
Tissue engineering
Regenerative medicine
title Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review
title_full Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review
title_fullStr Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review
title_full_unstemmed Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review
title_short Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review
title_sort computational methods for biofabrication in tissue engineering and regenerative medicine a literature review
topic Computational biology
Optimization via simulation
Biofabrication
Tissue engineering
Regenerative medicine
url http://www.sciencedirect.com/science/article/pii/S2001037023005111
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