Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP
Abstract The aim of this letter to the editor is to discuss the etiology and pathophysiology of chronic inflammatory demyelinating polyneuropathy (CIDP) in two patients, of whom one experienced a mildly symptomatic SARS-CoV-2 infection 2 months prior to onset of the CIDP (patient-1), whereas patient...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-12-01
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| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
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| Online Access: | https://doi.org/10.1186/s41983-022-00598-z |
| _version_ | 1811291992924094464 |
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| author | Josef Finsterer |
| author_facet | Josef Finsterer |
| author_sort | Josef Finsterer |
| collection | DOAJ |
| description | Abstract The aim of this letter to the editor is to discuss the etiology and pathophysiology of chronic inflammatory demyelinating polyneuropathy (CIDP) in two patients, of whom one experienced a mildly symptomatic SARS-CoV-2 infection 2 months prior to onset of the CIDP (patient-1), whereas patient-2 developed CIDP with bilateral facial palsy 19 days after receiving a shot of an RNA-based anti-SARS-CoV-2 vaccine. Causality between the SARS-CoV-2 infection and CIDP in patient-1 remains unsupported and the diagnosis CIDP in patient-2 remains questionable. Although delineation between CIDP and GBS is not clear cut, bilateral facial palsy and absence of proximal involvement suggest GBS rather than CIDP. |
| first_indexed | 2024-04-13T04:37:44Z |
| format | Article |
| id | doaj.art-58d79b4abe0e4166ad545871072f03c2 |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-04-13T04:37:44Z |
| publishDate | 2022-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-58d79b4abe0e4166ad545871072f03c22022-12-22T03:02:06ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292022-12-015811210.1186/s41983-022-00598-zAbsence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDPJosef Finsterer0Neurology and Neurophysiology CenterAbstract The aim of this letter to the editor is to discuss the etiology and pathophysiology of chronic inflammatory demyelinating polyneuropathy (CIDP) in two patients, of whom one experienced a mildly symptomatic SARS-CoV-2 infection 2 months prior to onset of the CIDP (patient-1), whereas patient-2 developed CIDP with bilateral facial palsy 19 days after receiving a shot of an RNA-based anti-SARS-CoV-2 vaccine. Causality between the SARS-CoV-2 infection and CIDP in patient-1 remains unsupported and the diagnosis CIDP in patient-2 remains questionable. Although delineation between CIDP and GBS is not clear cut, bilateral facial palsy and absence of proximal involvement suggest GBS rather than CIDP.https://doi.org/10.1186/s41983-022-00598-zSARS-CoV-2COVID-19VaccinationCIDPGuillain–Barre syndrome |
| spellingShingle | Josef Finsterer Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP The Egyptian Journal of Neurology, Psychiatry and Neurosurgery SARS-CoV-2 COVID-19 Vaccination CIDP Guillain–Barre syndrome |
| title | Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP |
| title_full | Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP |
| title_fullStr | Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP |
| title_full_unstemmed | Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP |
| title_short | Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP |
| title_sort | absence of proximal muscle weakness dysarthria and facial diplegia suggests guillain barre syndrome rather than cidp |
| topic | SARS-CoV-2 COVID-19 Vaccination CIDP Guillain–Barre syndrome |
| url | https://doi.org/10.1186/s41983-022-00598-z |
| work_keys_str_mv | AT joseffinsterer absenceofproximalmuscleweaknessdysarthriaandfacialdiplegiasuggestsguillainbarresyndromeratherthancidp |