Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome
Introduction Background: Thrombectomy improves outcomes in patients with basilar artery (BA) occlusion [1,2]. We hypothesized that the anatomic configuration of the BA bifurcation, classified as T‐ or Y‐shaped, may impact the outcome. Specifically, we expected that a T‐shaped BA would involve more d...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-11-01
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| Series: | Stroke: Vascular and Interventional Neurology |
| Online Access: | https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.068 |
| _version_ | 1797221207458709504 |
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| author | Mohammad Hossein Abbasi Ali Eltatawy Steven R. Messé Ashkan Mowla Charles J. Prestigiacomo Matthew S. Smith Michela Rosso Scott E. Kasner Peyman Shirani |
| author_facet | Mohammad Hossein Abbasi Ali Eltatawy Steven R. Messé Ashkan Mowla Charles J. Prestigiacomo Matthew S. Smith Michela Rosso Scott E. Kasner Peyman Shirani |
| author_sort | Mohammad Hossein Abbasi |
| collection | DOAJ |
| description | Introduction Background: Thrombectomy improves outcomes in patients with basilar artery (BA) occlusion [1,2]. We hypothesized that the anatomic configuration of the BA bifurcation, classified as T‐ or Y‐shaped, may impact the outcome. Specifically, we expected that a T‐shaped BA would involve more deep penetrating arteries of the midbrain and thalamus, leading to greater disability or death [3,4]. Methods In this 2‐center retrospective cohort study over seven years, we included patients with stroke due to distal BA occlusion and performed blinded classification of their BA anatomy as either T‐ or Y‐shaped [Figure 1]. The primary outcomes were favorable functional status at 90 days (modified Rankin Scale 0 – 2) and successful reperfusion (TICI scores 2B or 3). Results 70 patients (mean age 66 years, 36% women) were included. 38 had T‐ and 32 had Y‐shaped bifurcations. Baseline characteristics were similar for both groups, including demographics, treatment time, baseline NIHSS, THRIVE score, posterior circulation collateral score, and presence of tandem occlusion. Comparing the T‐ to the Y‐ shape, there was no difference in the likelihood of successful reperfusion (1.09 [0.52–2.27], p=1.00) nor 90‐day favorable mRS (0‐2) score (RR: 0.68 [0.37–1.27]; p=0.18). Similarly, mortality at 30 and 90 days were not significantly affected by the type of bifurcation. Conclusion The configuration of the basilar artery does not significantly impact reperfusion success or stroke outcome. |
| first_indexed | 2024-03-07T15:38:36Z |
| format | Article |
| id | doaj.art-58d7f042ad2e4bd38aa21c9fe6b52e89 |
| institution | Directory Open Access Journal |
| issn | 2694-5746 |
| language | English |
| last_indexed | 2024-04-24T13:01:46Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke: Vascular and Interventional Neurology |
| spelling | doaj.art-58d7f042ad2e4bd38aa21c9fe6b52e892024-04-05T10:51:56ZengWileyStroke: Vascular and Interventional Neurology2694-57462023-11-013S210.1161/SVIN.03.suppl_2.068Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcomeMohammad Hossein Abbasi0Ali Eltatawy1Steven R. Messé2Ashkan Mowla3Charles J. Prestigiacomo4Matthew S. Smith5Michela Rosso6Scott E. Kasner7Peyman Shirani8Department of Neurology University of Pennsylvania Philadelphia PA USADepartment of Neurology University of Cincinnati College of Medicine Cincinnati OH USADepartment of Neurology University of Pennsylvania Philadelphia PA USADepartment of Neurological Surgery University of Southern California CA USADepartment of Neurological Surgery University of Cincinnati College of Medicine Cincinnati OH USADepartment of Neurology University of Cincinnati College of Medicine Cincinnati OH USADepartment of Neurology University of Pennsylvania Philadelphia PA USADepartment of Neurology University of Pennsylvania Philadelphia PA USADepartment of Neurology University of Cincinnati College of Medicine Cincinnati OH USAIntroduction Background: Thrombectomy improves outcomes in patients with basilar artery (BA) occlusion [1,2]. We hypothesized that the anatomic configuration of the BA bifurcation, classified as T‐ or Y‐shaped, may impact the outcome. Specifically, we expected that a T‐shaped BA would involve more deep penetrating arteries of the midbrain and thalamus, leading to greater disability or death [3,4]. Methods In this 2‐center retrospective cohort study over seven years, we included patients with stroke due to distal BA occlusion and performed blinded classification of their BA anatomy as either T‐ or Y‐shaped [Figure 1]. The primary outcomes were favorable functional status at 90 days (modified Rankin Scale 0 – 2) and successful reperfusion (TICI scores 2B or 3). Results 70 patients (mean age 66 years, 36% women) were included. 38 had T‐ and 32 had Y‐shaped bifurcations. Baseline characteristics were similar for both groups, including demographics, treatment time, baseline NIHSS, THRIVE score, posterior circulation collateral score, and presence of tandem occlusion. Comparing the T‐ to the Y‐ shape, there was no difference in the likelihood of successful reperfusion (1.09 [0.52–2.27], p=1.00) nor 90‐day favorable mRS (0‐2) score (RR: 0.68 [0.37–1.27]; p=0.18). Similarly, mortality at 30 and 90 days were not significantly affected by the type of bifurcation. Conclusion The configuration of the basilar artery does not significantly impact reperfusion success or stroke outcome.https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.068 |
| spellingShingle | Mohammad Hossein Abbasi Ali Eltatawy Steven R. Messé Ashkan Mowla Charles J. Prestigiacomo Matthew S. Smith Michela Rosso Scott E. Kasner Peyman Shirani Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome Stroke: Vascular and Interventional Neurology |
| title | Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome |
| title_full | Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome |
| title_fullStr | Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome |
| title_full_unstemmed | Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome |
| title_short | Abstract 068: Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome |
| title_sort | abstract 068 basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome |
| url | https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.068 |
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