Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort
At the moment, several COVID-19 scoring systems have been developed. It is necessary to determine which one better predicts a poor outcome of the disease. We conducted a single-center prospective cohort study to validate four COVID-19 prognosis scores in adult patients with confirmed infection at wa...
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| Format: | Article |
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MDPI AG
2021-11-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/12/2211 |
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| author | Jaime Gil-Rodríguez Michel Martos-Ruiz José-Antonio Peregrina-Rivas Pablo Aranda-Laserna Alberto Benavente-Fernández Juan Melchor Emilio Guirao-Arrabal |
| author_facet | Jaime Gil-Rodríguez Michel Martos-Ruiz José-Antonio Peregrina-Rivas Pablo Aranda-Laserna Alberto Benavente-Fernández Juan Melchor Emilio Guirao-Arrabal |
| author_sort | Jaime Gil-Rodríguez |
| collection | DOAJ |
| description | At the moment, several COVID-19 scoring systems have been developed. It is necessary to determine which one better predicts a poor outcome of the disease. We conducted a single-center prospective cohort study to validate four COVID-19 prognosis scores in adult patients with confirmed infection at ward. These are National Early Warning Score (NEWS) 2, Lung Ultrasound Score (LUS), COVID-19 Worsening Score (COWS), and Spanish Society of Infectious Diseases and Clinical Microbiology score (SEIMC Score). Our outcomes were the combined variable “poor outcome” (non-invasive mechanical ventilation, intubation, intensive care unit admission, and death at 28 days) and death at 28 days. Scores were analysed using univariate logistic regression models, receiver operating characteristic curves, and areas under the curve. Eighty-one patients were included, from which 21 had a poor outcome, and 9 died. We found a statistically significant correlation between poor outcome and NEWS2, LUS > 15, and COWS. Death at 28 days was statistically correlated with NEWS2 and SEIMC Score although COWS also performs well. NEWS2, LUS, and COWS accurately predict poor outcome; and NEWS2, SEIMC Score, and COWS are useful for anticipating death at 28 days. Lung ultrasound is a diagnostic tool that should be included in COVID-19 patients evaluation. |
| first_indexed | 2024-03-10T04:19:55Z |
| format | Article |
| id | doaj.art-58e00b9b1d7444f7b9e98552ab7fbb92 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T04:19:55Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-58e00b9b1d7444f7b9e98552ab7fbb922023-11-23T07:52:57ZengMDPI AGDiagnostics2075-44182021-11-011112221110.3390/diagnostics11122211Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating CohortJaime Gil-Rodríguez0Michel Martos-Ruiz1José-Antonio Peregrina-Rivas2Pablo Aranda-Laserna3Alberto Benavente-Fernández4Juan Melchor5Emilio Guirao-Arrabal6Internal Medicine Unit, San Cecilio University Hospital, 18012 Granada, SpainInternal Medicine Unit, San Cecilio University Hospital, 18012 Granada, SpainInfectious Diseases Unit, San Cecilio University Hospital, 18012 Granada, SpainInternal Medicine Unit, San Cecilio University Hospital, 18012 Granada, SpainInternal Medicine Unit, San Cecilio University Hospital, 18012 Granada, SpainDepartment of Statistics and Operations Research, University of Granada, 18011 Granada, SpainInfectious Diseases Unit, San Cecilio University Hospital, 18012 Granada, SpainAt the moment, several COVID-19 scoring systems have been developed. It is necessary to determine which one better predicts a poor outcome of the disease. We conducted a single-center prospective cohort study to validate four COVID-19 prognosis scores in adult patients with confirmed infection at ward. These are National Early Warning Score (NEWS) 2, Lung Ultrasound Score (LUS), COVID-19 Worsening Score (COWS), and Spanish Society of Infectious Diseases and Clinical Microbiology score (SEIMC Score). Our outcomes were the combined variable “poor outcome” (non-invasive mechanical ventilation, intubation, intensive care unit admission, and death at 28 days) and death at 28 days. Scores were analysed using univariate logistic regression models, receiver operating characteristic curves, and areas under the curve. Eighty-one patients were included, from which 21 had a poor outcome, and 9 died. We found a statistically significant correlation between poor outcome and NEWS2, LUS > 15, and COWS. Death at 28 days was statistically correlated with NEWS2 and SEIMC Score although COWS also performs well. NEWS2, LUS, and COWS accurately predict poor outcome; and NEWS2, SEIMC Score, and COWS are useful for anticipating death at 28 days. Lung ultrasound is a diagnostic tool that should be included in COVID-19 patients evaluation.https://www.mdpi.com/2075-4418/11/12/2211SARS-CoV-2COVID-19lungultrasoundearly warning score |
| spellingShingle | Jaime Gil-Rodríguez Michel Martos-Ruiz José-Antonio Peregrina-Rivas Pablo Aranda-Laserna Alberto Benavente-Fernández Juan Melchor Emilio Guirao-Arrabal Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort Diagnostics SARS-CoV-2 COVID-19 lung ultrasound early warning score |
| title | Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort |
| title_full | Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort |
| title_fullStr | Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort |
| title_full_unstemmed | Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort |
| title_short | Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating Cohort |
| title_sort | lung ultrasound clinical and analytic scoring systems as prognostic tools in sars cov 2 pneumonia a validating cohort |
| topic | SARS-CoV-2 COVID-19 lung ultrasound early warning score |
| url | https://www.mdpi.com/2075-4418/11/12/2211 |
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