Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome

Objective: Subacromial impingement syndrome is the most common cause of shoulder pain and restriction in range of motion in the world. The aim of this study was to compare the efficacy of subacromial injection of ketorolac with the injection of corticosteroid for the treatment of subacromial impinge...

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Main Authors: Parisa Taheri, Farnaz Dehghan, Sahar Mousavi, Reza Solouki
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Research in Pharmacy Practice
Subjects:
Online Access:http://www.jrpp.net/article.asp?issn=2319-9644;year=2017;volume=6;issue=4;spage=223;epage=227;aulast=Taheri
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author Parisa Taheri
Farnaz Dehghan
Sahar Mousavi
Reza Solouki
author_facet Parisa Taheri
Farnaz Dehghan
Sahar Mousavi
Reza Solouki
author_sort Parisa Taheri
collection DOAJ
description Objective: Subacromial impingement syndrome is the most common cause of shoulder pain and restriction in range of motion in the world. The aim of this study was to compare the efficacy of subacromial injection of ketorolac with the injection of corticosteroid for the treatment of subacromial impingement syndrome. Methods: A total of forty patients were randomly allocated into two groups. Group A received 40 mg of methylprednisolone and Group B received 60 mg of ketorolac as a subacromial injection along with lidocaine. Each patient was evaluated in terms of visual analog scale (VAS) for evaluating pain and Constant's score for function evaluation (pain, activity level, and range of motion with standard goniometry). The patients were re-examined 1 and 3 months after intervention. All the patients educated for simple home exercise. Findings: At 1 and 3 months of follow-up, both treatment arms resulted in an increased range of motion and decreased pain. The difference between the groups was not statistically significant (P > 0.05). In ketorolac group, mean pre- and post-treatment (at 12 weeks) VAS scores were 8.6 (range, 3–9) and 4.5 (range 2–4), respectively. In steroid group, mean pre- and post-treatment (at 12 weeks) VAS scores were 8.3 (range, 3–10) and 3.9 (range, 0–7), respectively. The difference was statistically significant within groups at baseline and 1 (P < 0.001) and 3 (P < 0.001) months after the injection. Conclusion: Subacromial injection of ketorolac has an equivalent outcome to subacromial injection of corticosteroid. The use of ketorolac injections can substantially decrease the pain and increase the range of motion of the shoulder and could be a reasonable alternative in case of corticosteroid contraindications.
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spelling doaj.art-58e15f94424c4dd18d1f334e93f8e2002022-12-22T00:16:51ZengWolters Kluwer Medknow PublicationsJournal of Research in Pharmacy Practice2319-96442279-042X2017-01-016422322710.4103/jrpp.JRPP_17_57Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndromeParisa TaheriFarnaz DehghanSahar MousaviReza SoloukiObjective: Subacromial impingement syndrome is the most common cause of shoulder pain and restriction in range of motion in the world. The aim of this study was to compare the efficacy of subacromial injection of ketorolac with the injection of corticosteroid for the treatment of subacromial impingement syndrome. Methods: A total of forty patients were randomly allocated into two groups. Group A received 40 mg of methylprednisolone and Group B received 60 mg of ketorolac as a subacromial injection along with lidocaine. Each patient was evaluated in terms of visual analog scale (VAS) for evaluating pain and Constant's score for function evaluation (pain, activity level, and range of motion with standard goniometry). The patients were re-examined 1 and 3 months after intervention. All the patients educated for simple home exercise. Findings: At 1 and 3 months of follow-up, both treatment arms resulted in an increased range of motion and decreased pain. The difference between the groups was not statistically significant (P > 0.05). In ketorolac group, mean pre- and post-treatment (at 12 weeks) VAS scores were 8.6 (range, 3–9) and 4.5 (range 2–4), respectively. In steroid group, mean pre- and post-treatment (at 12 weeks) VAS scores were 8.3 (range, 3–10) and 3.9 (range, 0–7), respectively. The difference was statistically significant within groups at baseline and 1 (P < 0.001) and 3 (P < 0.001) months after the injection. Conclusion: Subacromial injection of ketorolac has an equivalent outcome to subacromial injection of corticosteroid. The use of ketorolac injections can substantially decrease the pain and increase the range of motion of the shoulder and could be a reasonable alternative in case of corticosteroid contraindications.http://www.jrpp.net/article.asp?issn=2319-9644;year=2017;volume=6;issue=4;spage=223;epage=227;aulast=TaheriCorticosteroidexternal impingementKetorolacnonsteroidal anti-inflammatory drugsubacromial
spellingShingle Parisa Taheri
Farnaz Dehghan
Sahar Mousavi
Reza Solouki
Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
Journal of Research in Pharmacy Practice
Corticosteroid
external impingement
Ketorolac
nonsteroidal anti-inflammatory drug
subacromial
title Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
title_full Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
title_fullStr Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
title_full_unstemmed Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
title_short Comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
title_sort comparison of subacromial ketorolac injection zversus corticosteroid injection in the treatment of shoulder impingement syndrome
topic Corticosteroid
external impingement
Ketorolac
nonsteroidal anti-inflammatory drug
subacromial
url http://www.jrpp.net/article.asp?issn=2319-9644;year=2017;volume=6;issue=4;spage=223;epage=227;aulast=Taheri
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AT saharmousavi comparisonofsubacromialketorolacinjectionzversuscorticosteroidinjectioninthetreatmentofshoulderimpingementsyndrome
AT rezasolouki comparisonofsubacromialketorolacinjectionzversuscorticosteroidinjectioninthetreatmentofshoulderimpingementsyndrome