Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth
The Ewing sarcoma family of tumors is a group of malignant small round blue cell tumors (SRBCTs) that affect children, adolescents, and young adults. The tumors are characterized by reciprocal chromosomal translocations that generate chimeric fusion oncogenes, the most common of which is EWSR1-FLI1....
Main Authors: | Elena Vasileva, Mikako Warren, Timothy J Triche, James F Amatruda |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/69734 |
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