GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris.
The well-studied DNA replication origins of the model budding and fission yeasts are A/T-rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated with transcription start sites. Here we show that an industrially important methylotrophic...
Main Authors: | , , , , , , , , |
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格式: | 文件 |
语言: | English |
出版: |
Public Library of Science (PLoS)
2014-03-01
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丛编: | PLoS Genetics |
在线阅读: | http://europepmc.org/articles/PMC3945215?pdf=render |