GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris.

The well-studied DNA replication origins of the model budding and fission yeasts are A/T-rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated with transcription start sites. Here we show that an industrially important methylotrophic...

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Main Authors: Ivan Liachko, Rachel A Youngblood, Kyle Tsui, Kerry L Bubb, Christine Queitsch, M K Raghuraman, Corey Nislow, Bonita J Brewer, Maitreya J Dunham
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2014-03-01
丛编:PLoS Genetics
在线阅读:http://europepmc.org/articles/PMC3945215?pdf=render