GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris.

GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris.

The well-studied DNA replication origins of the model budding and fission yeasts are A/T-rich elements. However, unlike their yeast counterparts, both plant and metazoan origins are G/C-rich and are associated with transcription start sites. Here we show that an industrially important methylotrophic...

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Hlavní autoři: Ivan Liachko, Rachel A Youngblood, Kyle Tsui, Kerry L Bubb, Christine Queitsch, M K Raghuraman, Corey Nislow, Bonita J Brewer, Maitreya J Dunham
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2014-03-01
Edice:PLoS Genetics
On-line přístup:http://europepmc.org/articles/PMC3945215?pdf=render

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http://europepmc.org/articles/PMC3945215?pdf=render

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