Are brain MRI abnormalities associated with the semiology of functional seizures?
Abstract Purpose To investigate whether radiologically apparent brain magnetic resonance imaging (MRI) abnormalities are associated with the functional seizure (FS) semiology. Methods All patients with a diagnosis of FS at the epilepsy centers at Shiraz University of Medical Sciences, Iran; Aichi Me...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-02-01
|
| Series: | Brain and Behavior |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/brb3.2882 |
| _version_ | 1811164241548279808 |
|---|---|
| author | Ali A. Asadi‐Pooya Wesley T. Kerr Ioannis Karakis Kousuke Kanemoto Anilu Daza‐Restrepo Mohsen Farazdaghi Faith J. Horbatch Nicholas J. Beimer Dawn E. Eliashiv Aida Risman Yuko Sugimoto Brenda Giagante |
| author_facet | Ali A. Asadi‐Pooya Wesley T. Kerr Ioannis Karakis Kousuke Kanemoto Anilu Daza‐Restrepo Mohsen Farazdaghi Faith J. Horbatch Nicholas J. Beimer Dawn E. Eliashiv Aida Risman Yuko Sugimoto Brenda Giagante |
| author_sort | Ali A. Asadi‐Pooya |
| collection | DOAJ |
| description | Abstract Purpose To investigate whether radiologically apparent brain magnetic resonance imaging (MRI) abnormalities are associated with the functional seizure (FS) semiology. Methods All patients with a diagnosis of FS at the epilepsy centers at Shiraz University of Medical Sciences, Iran; Aichi Medical University Hospital, Japan; University of Michigan, USA; University of California, Los Angeles, USA; Emory University School of Medicine, USA; and Hospital el Cruce, Argentina, were studied. Results One hundred patients were included; 77 (77%) had motor functional seizures. Lobar location of brain abnormality did not have an association with the semiology (p = .83). There was no significant difference between ictal behaviors in patients with frontal or parietal lesions compared to those with temporal or occipital lesions. Conclusion There were no associations between functional seizure ictal behaviors and locations of the radiologically apparent brain MRI abnormalities. Further studies are needed to evaluate the underpinnings of varying behaviors in FS. |
| first_indexed | 2024-04-10T15:19:20Z |
| format | Article |
| id | doaj.art-58e77f00726e469bb4d94673878034f0 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-04-10T15:19:20Z |
| publishDate | 2023-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-58e77f00726e469bb4d94673878034f02023-02-14T16:52:41ZengWileyBrain and Behavior2162-32792023-02-01132n/an/a10.1002/brb3.2882Are brain MRI abnormalities associated with the semiology of functional seizures?Ali A. Asadi‐Pooya0Wesley T. Kerr1Ioannis Karakis2Kousuke Kanemoto3Anilu Daza‐Restrepo4Mohsen Farazdaghi5Faith J. Horbatch6Nicholas J. Beimer7Dawn E. Eliashiv8Aida Risman9Yuko Sugimoto10Brenda Giagante11Epilepsy Research Center Shiraz University of Medical Sciences Shiraz IranDepartment of Neurology University of Michigan Ann Arbor MichiganDepartment of Neurology Emory University School of Medicine Atlanta GeorgiaNeuropsychiatric Department Aichi Medical University Nagakute Aichi JapanENyS CONICET – Neuroscience and Epilepsy Service El Cruce Hospital “Dr. Néstor Kirchner,” Buenos Aires ArgentinaEpilepsy Research Center Shiraz University of Medical Sciences Shiraz IranDepartment of Neurology University of Michigan Ann Arbor MichiganDepartment of Neurology University of Michigan Ann Arbor MichiganDepartment of Neurology David Geffen School of Medicine at the University of California Los Angeles CaliforniaDepartment of Neurology Emory University School of Medicine Atlanta GeorgiaNeuropsychiatric Department Aichi Medical University Nagakute Aichi JapanENyS CONICET – Neuroscience and Epilepsy Service El Cruce Hospital “Dr. Néstor Kirchner,” Buenos Aires ArgentinaAbstract Purpose To investigate whether radiologically apparent brain magnetic resonance imaging (MRI) abnormalities are associated with the functional seizure (FS) semiology. Methods All patients with a diagnosis of FS at the epilepsy centers at Shiraz University of Medical Sciences, Iran; Aichi Medical University Hospital, Japan; University of Michigan, USA; University of California, Los Angeles, USA; Emory University School of Medicine, USA; and Hospital el Cruce, Argentina, were studied. Results One hundred patients were included; 77 (77%) had motor functional seizures. Lobar location of brain abnormality did not have an association with the semiology (p = .83). There was no significant difference between ictal behaviors in patients with frontal or parietal lesions compared to those with temporal or occipital lesions. Conclusion There were no associations between functional seizure ictal behaviors and locations of the radiologically apparent brain MRI abnormalities. Further studies are needed to evaluate the underpinnings of varying behaviors in FS.https://doi.org/10.1002/brb3.2882magnetic resonance imaging (MRI)neuropsychiatricspsychiatric disorders |
| spellingShingle | Ali A. Asadi‐Pooya Wesley T. Kerr Ioannis Karakis Kousuke Kanemoto Anilu Daza‐Restrepo Mohsen Farazdaghi Faith J. Horbatch Nicholas J. Beimer Dawn E. Eliashiv Aida Risman Yuko Sugimoto Brenda Giagante Are brain MRI abnormalities associated with the semiology of functional seizures? Brain and Behavior magnetic resonance imaging (MRI) neuropsychiatrics psychiatric disorders |
| title | Are brain MRI abnormalities associated with the semiology of functional seizures? |
| title_full | Are brain MRI abnormalities associated with the semiology of functional seizures? |
| title_fullStr | Are brain MRI abnormalities associated with the semiology of functional seizures? |
| title_full_unstemmed | Are brain MRI abnormalities associated with the semiology of functional seizures? |
| title_short | Are brain MRI abnormalities associated with the semiology of functional seizures? |
| title_sort | are brain mri abnormalities associated with the semiology of functional seizures |
| topic | magnetic resonance imaging (MRI) neuropsychiatrics psychiatric disorders |
| url | https://doi.org/10.1002/brb3.2882 |
| work_keys_str_mv | AT aliaasadipooya arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT wesleytkerr arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT ioanniskarakis arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT kousukekanemoto arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT aniludazarestrepo arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT mohsenfarazdaghi arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT faithjhorbatch arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT nicholasjbeimer arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT dawneeliashiv arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT aidarisman arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT yukosugimoto arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures AT brendagiagante arebrainmriabnormalitiesassociatedwiththesemiologyoffunctionalseizures |