Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria

Effect of nevirapine, efavirenz and lopinavir/ritonavir on the therapeutic concentration and toxicity of lumefantrine in people living with HIV at Lagos University Teaching Hospital, Nigeria

Patients living with HIV in malarial endemic regions may experience clinically significant drug interaction between antiretroviral and antimalarial drugs. Effects of nevirapine (NVP), efavirenz (EFV) and lopinavir/ritonavir (LPVr) on lumefantrine (LM) therapeutic concentrations and toxicity were eva...

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Bibliographic Details
Main Authors: Sikiru Olatunji Usman, Ibrahim Adekunle Oreagba, Akinwumi Akinyinka Akinyede, Esther Oluwatoyin Agbaje, Moshood Olusola Akinleye, Adaobi Goodness Onwujuobi, Chioma Ken-Owotor, Olatunbosun Adeuja, Tosin Ogunfowokan, Segun Kogbe, Emmanuel Tope Owolabi, Hannah Adeniji, Abdul Wasiu Busari, Olayinka Olayiwola Hassan, Ganiu Abideen, Alani Sulaimon Akanmu
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Journal of Pharmacological Sciences
Subjects:
Lumefantrine
Antiretroviral drugs
Therapeutic concentrations
Malaria
HIV
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300785

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http://www.sciencedirect.com/science/article/pii/S1347861320300785

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