Gene expression profiles and bioinformatics analysis of insulin‐like growth factor‐1 promotion of osteogenic differentiation

Gene expression profiles and bioinformatics analysis of insulin‐like growth factor‐1 promotion of osteogenic differentiation

Abstract Background Insulin‐like growth factor‐1 (IGF‐1) promotes osteoblast differentiation and mineralization. The objective of this study was to investigate the effects of IGF‐1 on proliferation, mineralization, alkaline phosphatase (ALP) synthesis, and gene expression of osteoblast differentiati...

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Bibliographic Details
Main Authors: Yashuai Yuan, Ruimeng Duan, Baolin Wu, Wei Huang, Xiuzhi Zhang, Mingjia Qu, Tao Liu, Xiaobing Yu
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
IGF‐1
MC3T3‐E1 cells
Proliferation
RNA‐seq
Online Access:https://doi.org/10.1002/mgg3.921

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