Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata
Abstract Four hitherto unknown prenylated coumarins, namely 6″-O-β-d-apiofuranosylapterin (1), 4′-O-isobutyroylpeguangxienin (2), 6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin (3), and 6-hydroxycoumurrayin (4), were isolated from the ethanol extract of Heracleum stenopterum, Peucedanum praeruptorum,...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2016-09-01
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| Series: | Natural Products and Bioprospecting |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1007/s13659-016-0107-5 |
| _version_ | 1828790245759385600 |
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| author | Xiang-Mei Li Xian-Jun Jiang Ku Yang Li-Xia Wang Shi-Zhen Wen Fei Wang |
| author_facet | Xiang-Mei Li Xian-Jun Jiang Ku Yang Li-Xia Wang Shi-Zhen Wen Fei Wang |
| author_sort | Xiang-Mei Li |
| collection | DOAJ |
| description | Abstract Four hitherto unknown prenylated coumarins, namely 6″-O-β-d-apiofuranosylapterin (1), 4′-O-isobutyroylpeguangxienin (2), 6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin (3), and 6-hydroxycoumurrayin (4), were isolated from the ethanol extract of Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata, respectively. Their chemical structures were established on the basis of extensive spectroscopic analysis. Compound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW-480) with IC50 values ranging from 15.9 to 23.2 μM. Graphical Abstract |
| first_indexed | 2024-12-12T01:27:03Z |
| format | Article |
| id | doaj.art-58ee654904264c7f9c45431c3c4fc6b4 |
| institution | Directory Open Access Journal |
| issn | 2192-2195 2192-2209 |
| language | English |
| last_indexed | 2024-12-12T01:27:03Z |
| publishDate | 2016-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Natural Products and Bioprospecting |
| spelling | doaj.art-58ee654904264c7f9c45431c3c4fc6b42022-12-22T00:43:04ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092016-09-016523323710.1007/s13659-016-0107-5Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculataXiang-Mei Li0Xian-Jun Jiang1Ku Yang2Li-Xia Wang3Shi-Zhen Wen4Fei Wang5BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.Abstract Four hitherto unknown prenylated coumarins, namely 6″-O-β-d-apiofuranosylapterin (1), 4′-O-isobutyroylpeguangxienin (2), 6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin (3), and 6-hydroxycoumurrayin (4), were isolated from the ethanol extract of Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata, respectively. Their chemical structures were established on the basis of extensive spectroscopic analysis. Compound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW-480) with IC50 values ranging from 15.9 to 23.2 μM. Graphical Abstracthttp://link.springer.com/article/10.1007/s13659-016-0107-5Heracleum stenopterumPeucedanum praeruptorumClausena lansiumMurraya paniculataPrenylated coumarinCytotoxicity |
| spellingShingle | Xiang-Mei Li Xian-Jun Jiang Ku Yang Li-Xia Wang Shi-Zhen Wen Fei Wang Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata Natural Products and Bioprospecting Heracleum stenopterum Peucedanum praeruptorum Clausena lansium Murraya paniculata Prenylated coumarin Cytotoxicity |
| title | Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata |
| title_full | Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata |
| title_fullStr | Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata |
| title_full_unstemmed | Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata |
| title_short | Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata |
| title_sort | prenylated coumarins from heracleum stenopterum peucedanum praeruptorum clausena lansium and murraya paniculata |
| topic | Heracleum stenopterum Peucedanum praeruptorum Clausena lansium Murraya paniculata Prenylated coumarin Cytotoxicity |
| url | http://link.springer.com/article/10.1007/s13659-016-0107-5 |
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