<i>Clostridioides difficile</i> Flagellin Activates the Intracellular NLRC4 Inflammasome

<i>Clostridioides difficile</i> Flagellin Activates the Intracellular NLRC4 Inflammasome

<i>Clostridioides difficile</i> (<i>C. difficile</i>), is a major cause of nosocomial diarrhea and colitis. <i>C. difficile</i> flagellin FliC contributes toxins to gut inflammation by interacting with the immune Toll-like receptor 5 (TLR5) to activate nuclear fac...

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Bibliographic Details
Main Authors: Hiba Chebly, Jean-Christophe Marvaud, Layale Safa, Assem Khalil Elkak, Philippe Hussein Kobeissy, Imad Kansau, Cécile Larrazet
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Clostridioides difficile</i>
flagellin
inflammasome
NLRC4
pro-caspase-1
gasdermin
Online Access:https://www.mdpi.com/1422-0067/23/20/12366

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