Highly Water-Soluble Solid Dispersions of Honokiol: Preparation, Solubility, and Bioavailability Studies and Anti-Tumor Activity Evaluation

Highly Water-Soluble Solid Dispersions of Honokiol: Preparation, Solubility, and Bioavailability Studies and Anti-Tumor Activity Evaluation

Honokiol (HK), a well-tolerated natural product, has many multiple pharmacological activities. However, its poor water solubility and low bioavailability limit its clinical application and development. The aim of this research was to prepare the solid dispersion (SD) formulation of honokiol (HK) wit...

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Bibliographic Details
Main Authors: Li Wang, Weiwei Wu, Lingling Wang, Lu Wang, Xiuhua Zhao
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Pharmaceutics
Subjects:
honokiol
solid dispersion
solubility
bioavailability
antitumor activity
Online Access:https://www.mdpi.com/1999-4923/11/11/573

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