Factors influencing the immunogenicity of influenza vaccines

Annual vaccination is the best prevention of influenza. However, the immunogenicity of influenza vaccines varies among different populations. It is important to fully identify the factors that may affect the immunogenicity of the vaccines to provide best protection for vaccine recipients. This paper...

Full description

Bibliographic Details
Main Authors: Simin Wen, Zhengyu Wu, Shuyi Zhong, Mao Li, Yuelong Shu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-08-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2021.1875761
_version_ 1797677209288179712
author Simin Wen
Zhengyu Wu
Shuyi Zhong
Mao Li
Yuelong Shu
author_facet Simin Wen
Zhengyu Wu
Shuyi Zhong
Mao Li
Yuelong Shu
author_sort Simin Wen
collection DOAJ
description Annual vaccination is the best prevention of influenza. However, the immunogenicity of influenza vaccines varies among different populations. It is important to fully identify the factors that may affect the immunogenicity of the vaccines to provide best protection for vaccine recipients. This paper reviews the factors that may influence the immunogenicity of influenza vaccines from the aspects of vaccine factors, adjuvants, individual factors, repeated vaccination, and genetic factors. The confirmed or hypothesized molecular mechanisms of these factors have also been briefly summarized.
first_indexed 2024-03-11T22:41:47Z
format Article
id doaj.art-58f0709bf19042d69b62dd2cb8d7cfe2
institution Directory Open Access Journal
issn 2164-5515
2164-554X
language English
last_indexed 2024-03-11T22:41:47Z
publishDate 2021-08-01
publisher Taylor & Francis Group
record_format Article
series Human Vaccines & Immunotherapeutics
spelling doaj.art-58f0709bf19042d69b62dd2cb8d7cfe22023-09-22T08:51:53ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-08-011782706271810.1080/21645515.2021.18757611875761Factors influencing the immunogenicity of influenza vaccinesSimin Wen0Zhengyu Wu1Shuyi Zhong2Mao Li3Yuelong Shu4Sun Yat-sen UniversitySun Yat-sen UniversitySun Yat-sen UniversitySun Yat-sen UniversitySun Yat-sen UniversityAnnual vaccination is the best prevention of influenza. However, the immunogenicity of influenza vaccines varies among different populations. It is important to fully identify the factors that may affect the immunogenicity of the vaccines to provide best protection for vaccine recipients. This paper reviews the factors that may influence the immunogenicity of influenza vaccines from the aspects of vaccine factors, adjuvants, individual factors, repeated vaccination, and genetic factors. The confirmed or hypothesized molecular mechanisms of these factors have also been briefly summarized.http://dx.doi.org/10.1080/21645515.2021.1875761influenzavaccineimmunogenicityimmune response
spellingShingle Simin Wen
Zhengyu Wu
Shuyi Zhong
Mao Li
Yuelong Shu
Factors influencing the immunogenicity of influenza vaccines
Human Vaccines & Immunotherapeutics
influenza
vaccine
immunogenicity
immune response
title Factors influencing the immunogenicity of influenza vaccines
title_full Factors influencing the immunogenicity of influenza vaccines
title_fullStr Factors influencing the immunogenicity of influenza vaccines
title_full_unstemmed Factors influencing the immunogenicity of influenza vaccines
title_short Factors influencing the immunogenicity of influenza vaccines
title_sort factors influencing the immunogenicity of influenza vaccines
topic influenza
vaccine
immunogenicity
immune response
url http://dx.doi.org/10.1080/21645515.2021.1875761
work_keys_str_mv AT siminwen factorsinfluencingtheimmunogenicityofinfluenzavaccines
AT zhengyuwu factorsinfluencingtheimmunogenicityofinfluenzavaccines
AT shuyizhong factorsinfluencingtheimmunogenicityofinfluenzavaccines
AT maoli factorsinfluencingtheimmunogenicityofinfluenzavaccines
AT yuelongshu factorsinfluencingtheimmunogenicityofinfluenzavaccines